SCOP 1.75: Family d.15.2.2: PB1 domain

Lineage for Family d.15.2.2: PB1 domain

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.2: CAD & PB1 domains [54277] (2 families)
   contain extra helix; similar heterodimerization modes; possibly related to the ubiquitin-like superfamily

5. Family d.15.2.2: PB1 domain [64225] (10 proteins)
   Pfam PF00564
   forms heterodimers, although not all PB1 domain pairs associate.

Proteins:

1. Bud emergence mediator Bemp1 [64226] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64227] (2 PDB entries)

2. Cell division control protein 24, CDC24, C-terminal domain [89834] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89835] (3 PDB entries)

3. Mitogen activated protein kinase kinase 5, Map2k5 [117827] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [142975] (1 PDB entry)
      Uniprot Q13163 4-108

   2. Species Mouse (Mus musculus) [TaxId:10090] [117828] (1 PDB entry)
      Uniprot Q9D222 7-107

4. Mitogen-activated protein kinase kinase kinase 2, MEKK 2 [142976] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142977] (2 PDB entries)
     Uniprot Q9Y2U5 42-123! Uniprot Q9Y2U5 43-132

5. Mitogen-activated protein kinase kinase kinase 3, MEKK 3 [142978] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142979] (2 PDB entries)
     Uniprot Q99759 42-123! Uniprot Q99759 43-122

6. Neutrophil cytosol factor 2 (p67phox component of NADPH oxidase) [102790] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102791] (1 PDB entry)

7. Neutrophil cytosol factor 4 (p40phox component of NADPH oxidase) [102792] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102793] (1 PDB entry)

8. Next to BRCA1 gene 1 protein, NBR1 (KIAA0049) [117829] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [117830] (2 PDB entries)
     Uniprot Q14596 1-85

9. Partitioning defective-6 homolog alpha, PAR-6 alpha [117831] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [117832] (1 PDB entry)
     Uniprot Q9NPB6 14-95

10. Protein kinase C, iota type [110804] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [110805] (2 PDB entries)
      Uniprot P41743 16-98
      Uniprot P41743 16-99
      Uniprot P41743 16-98 ! Uniprot P41743 16-99

More info for Family d.15.2.2: PB1 domain

Timeline for Family d.15.2.2: PB1 domain:

• Family d.15.2.2: PB1 domain first appeared in SCOP 1.57
  
• Family d.15.2.2: PB1 domain appears in SCOP 1.73
  
• Family d.15.2.2: PB1 domain appears in SCOPe 2.01
  
• Family d.15.2.2: PB1 domain appears in the current release, SCOPe 2.08