Lineage for Protein: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.97: Cytidine deaminase-like [53926] (2 superfamilies)
    core: alpha-beta(2)-(alpha-beta)2; 3 layers (a/b/a); mixed beta-sheet of 4 strands, order 2134; strand 1 is antiparallel to the rest
  4. Superfamily c.97.1: Cytidine deaminase-like [53927] (7 families) (S)
    contains extra C-terminal strand 5, order 21345
  5. Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64198] (2 proteins)
    duplication: consists of two domains of this fold with extra secondary structures within and in between the two core motifs
  6. Protein AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64199] (3 species)

Species:

  1. Chicken (Gallus gallus) [TaxId:9031] [64200] (9 PDB entries)
    Uniprot P31335
    1. Domains for 1g8m:
      1. Domain d1g8ma2: 1g8m A:201-593 [60372]
        Other proteins in same PDB: d1g8ma1, d1g8mb1
        complexed with g, k
      2. Domain d1g8mb2: 1g8m B:201-593 [60374]
        Other proteins in same PDB: d1g8ma1, d1g8mb1
        complexed with g, k
    2. Domains for 1m9n:
      1. Domain d1m9na2: 1m9n A:201-593 [78871]
        Other proteins in same PDB: d1m9na1, d1m9nb1
        complexed with amz, k, xmp
      2. Domain d1m9nb2: 1m9n B:201-593 [78873]
        Other proteins in same PDB: d1m9na1, d1m9nb1
        complexed with amz, k, xmp
    3. Domains for 1oz0:
      1. Domain d1oz0a2: 1oz0 A:201-593 [93777]
        Other proteins in same PDB: d1oz0a1, d1oz0b1
        complexed with k, ms1, po4
      2. Domain d1oz0b2: 1oz0 B:201-593 [93779]
        Other proteins in same PDB: d1oz0a1, d1oz0b1
        complexed with k, ms1, po4
    4. Domains for 1thz:
      1. Domain d1thza2: 1thz A:201-593 [106922]
        Other proteins in same PDB: d1thza1, d1thzb1
        complexed with 326, k
      2. Domain d1thzb2: 1thz B:201-593 [106924]
        Other proteins in same PDB: d1thza1, d1thzb1
        complexed with 326, k
    5. Domains for 2b0w:
      1. Domain d2b0wa2: 2b0w A:201-593 [303535]
        Other proteins in same PDB: d2b0wa1, d2b0wb1
        automated match to d1g8ma2
        complexed with 203, k
      2. Domain d2b0wb2: 2b0w B:201-593 [303537]
        Other proteins in same PDB: d2b0wa1, d2b0wb1
        automated match to d1g8ma2
        complexed with 203, k
    6. Domains for 2b1g:
      1. Domain d2b1ga2: 2b1g A:201-593 [203528]
        Other proteins in same PDB: d2b1ga1, d2b1gb1, d2b1gc1, d2b1gd1
        automated match to d1g8ma2
        complexed with 13a, k, po4
      2. Domain d2b1gb2: 2b1g B:201-593 [203530]
        Other proteins in same PDB: d2b1ga1, d2b1gb1, d2b1gc1, d2b1gd1
        automated match to d1g8ma2
        complexed with 13a, k, po4
      3. Domain d2b1gc2: 2b1g C:201-593 [203532]
        Other proteins in same PDB: d2b1ga1, d2b1gb1, d2b1gc1, d2b1gd1
        automated match to d1g8ma2
        complexed with 13a, k, po4
      4. Domain d2b1gd2: 2b1g D:201-593 [203534]
        Other proteins in same PDB: d2b1ga1, d2b1gb1, d2b1gc1, d2b1gd1
        automated match to d1g8ma2
        complexed with 13a, k, po4
    7. Domains for 2b1i:
      1. Domain d2b1ia2: 2b1i A:201-593 [203536]
        Other proteins in same PDB: d2b1ia1, d2b1ib1
        automated match to d1g8ma2
        complexed with 93a, k
      2. Domain d2b1ib2: 2b1i B:201-593 [203538]
        Other proteins in same PDB: d2b1ia1, d2b1ib1
        automated match to d1g8ma2
        complexed with 93a, k
    8. Domains for 2iu0:
      1. Domain d2iu0a2: 2iu0 A:201-593 [204853]
        Other proteins in same PDB: d2iu0a1, d2iu0b1
        automated match to d1g8ma2
        complexed with 203, k
      2. Domain d2iu0b2: 2iu0 B:201-593 [204855]
        Other proteins in same PDB: d2iu0a1, d2iu0b1
        automated match to d1g8ma2
        complexed with 203, k
    9. Domains for 2iu3:
      1. Domain d2iu3a2: 2iu3 A:201-593 [204857]
        Other proteins in same PDB: d2iu3a1, d2iu3b1
        automated match to d1g8ma2
        complexed with 203, k
      2. Domain d2iu3b2: 2iu3 B:201-593 [204859]
        Other proteins in same PDB: d2iu3a1, d2iu3b1
        automated match to d1g8ma2
        complexed with 203, k
  2. Human (Homo sapiens) [TaxId:9606] [102716] (3 PDB entries)
    1. Domains for 1p4r:
      1. Domain d1p4ra2: 1p4r A:201-592 [94114]
        Other proteins in same PDB: d1p4ra1, d1p4rb1
        complexed with 354, amz, k, xmp
      2. Domain d1p4rb2: 1p4r B:201-592 [94116]
        Other proteins in same PDB: d1p4ra1, d1p4rb1
        complexed with 354, amz, k, xmp
    2. Domains for 1pkx:
      1. Domain d1pkxa2: 1pkx A:201-592 [94839]
        Other proteins in same PDB: d1pkxa1, d1pkxb1, d1pkxc1, d1pkxd1
        complexed with k, xmp
      2. Domain d1pkxb2: 1pkx B:201-592 [94841]
        Other proteins in same PDB: d1pkxa1, d1pkxb1, d1pkxc1, d1pkxd1
        complexed with k, xmp
      3. Domain d1pkxc2: 1pkx C:201-592 [94843]
        Other proteins in same PDB: d1pkxa1, d1pkxb1, d1pkxc1, d1pkxd1
        complexed with k, xmp
      4. Domain d1pkxd2: 1pkx D:201-592 [94845]
        Other proteins in same PDB: d1pkxa1, d1pkxb1, d1pkxc1, d1pkxd1
        complexed with k, xmp
    3. Domains for 1pl0:
      1. Domain d1pl0a2: 1pl0 A:201-592 [94847]
        Other proteins in same PDB: d1pl0a1, d1pl0b1, d1pl0c1, d1pl0d1
        complexed with amz, bw2, k, xmp
      2. Domain d1pl0b2: 1pl0 B:201-592 [94849]
        Other proteins in same PDB: d1pl0a1, d1pl0b1, d1pl0c1, d1pl0d1
        complexed with amz, bw2, k, xmp
      3. Domain d1pl0c2: 1pl0 C:201-592 [94851]
        Other proteins in same PDB: d1pl0a1, d1pl0b1, d1pl0c1, d1pl0d1
        complexed with amz, bw2, k, xmp
      4. Domain d1pl0d2: 1pl0 D:201-592 [94853]
        Other proteins in same PDB: d1pl0a1, d1pl0b1, d1pl0c1, d1pl0d1
        complexed with amz, bw2, k, xmp
  3. Thermotoga maritima [TaxId:2336] [142844] (1 PDB entry)
    Uniprot Q9X0X6 158-452

More info for Protein AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC from c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

Timeline for Protein AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC from c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC: