SCOP 1.75: Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like

Lineage for Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (57 families)

5. Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like [64117] (4 proteins)
   contains additional N-terminal beta-sandwich domain

Proteins:

1. Hypothetical protein FLJ20628 [142583] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142584] (1 PDB entry)
     Uniprot Q9BVS5 149-472

2. Hypothetical protein Ta0852 [142585] (1 species)
   forms dimer similar to half-tetramer of the other members but with swapped N-terminal domains; variant topology of the N-terminal domain

   • Species Thermoplasma acidophilum [TaxId:2303] [142586] (1 PDB entry)
     Uniprot Q9HJW1 6-255

3. Hypothetical protein TM0748 [102573] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [102574] (1 PDB entry)

4. Probable methyltransferase Rv2118c [64118] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [64119] (1 PDB entry)

More info for Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like

Timeline for Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like:

• Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like first appeared in SCOP 1.57, called Family c.66.1.13: Probable methyltransferase Rv2118c
  
• Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like appears in SCOP 1.73
  
• Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like appears in SCOPe 2.01
  
• Family c.66.1.13: tRNA(1-methyladenosine) methyltransferase-like appears in the current release, SCOPe 2.08