Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like |
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) binds cofactor molecules in the opposite direction than classical Rossmann fold |
Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins) silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain |
Protein Sirt2 histone deacetylase [63987] (1 species) |
Human (Homo sapiens) [TaxId:9606] [63988] (23 PDB entries) |
Domain d1j8fa_: 1j8f A: [62738] complexed with zn |
Domain d1j8fb_: 1j8f B: [62739] complexed with zn |
Domain d1j8fc_: 1j8f C: [62740] complexed with zn |
Domain d4rmga1: 4rmg A:56-356 [269355] Other proteins in same PDB: d4rmga2 automated match to d1j8fc_ complexed with 3te, nad, zn |
Domain d4rmha_: 4rmh A: [269351] automated match to d1j8fc_ complexed with 3te, zn |
Domain d4rmia_: 4rmi A: [269357] automated match to d1j8fc_ complexed with 3tk, zn |
Domain d4rmja1: 4rmj A:56-355 [269352] Other proteins in same PDB: d4rmja2, d4rmjb2 automated match to d1j8fc_ complexed with ar6, edo, na, nca, peg, pge, zn |
Domain d4rmjb1: 4rmj B:56-355 [269356] Other proteins in same PDB: d4rmja2, d4rmjb2 automated match to d1j8fc_ complexed with ar6, edo, na, nca, peg, pge, zn |
Domain d4y6qa_: 4y6q A: [310100] automated match to d1j8fc_ complexed with omr, zn |
Domain d4y6qb_: 4y6q B: [310101] automated match to d1j8fc_ complexed with omr, zn |
Domain d4y6qc_: 4y6q C: [310102] automated match to d1j8fc_ complexed with omr, zn |
Domain d4y6qd_: 4y6q D: [310103] automated match to d1j8fc_ complexed with omr, zn |
Domain d5d7oa_: 5d7o A: [310390] automated match to d5dy4a_ complexed with ar6, pge, zn |
Domain d5d7ob_: 5d7o B: [310391] automated match to d5dy4a_ complexed with ar6, pge, zn |
Domain d5d7pa1: 5d7p A:56-355 [310392] Other proteins in same PDB: d5d7pa2 automated match to d5dy4a_ complexed with ar6, ocz, peg, zn |
Domain d5d7pb_: 5d7p B: [310394] Other proteins in same PDB: d5d7pa2 automated match to d5dy4a_ complexed with ar6, ocz, peg, zn |
Domain d5d7qa1: 5d7q A:56-354 [310395] Other proteins in same PDB: d5d7qa2 automated match to d5dy4a_ complexed with 4i5, ar6, zn |
Domain d5d7qb_: 5d7q B: [310397] Other proteins in same PDB: d5d7qa2 automated match to d5dy4a_ complexed with 4i5, ar6, zn |
Domain d5dy4a1: 5dy4 A:56-356 [280350] Other proteins in same PDB: d5dy4a2 automated match to d1j8fc_ complexed with 5gn, nad, zn |
Domain d5dy5a1: 5dy5 A:56-356 [313470] Other proteins in same PDB: d5dy5a2 automated match to d1j8fc_ complexed with 5gr, bu3, edo, epe, zn |
Domain d5g4ca_: 5g4c A: [333699] automated match to d1j8fa_ complexed with cna, zn |
Domain d5g4cb_: 5g4c B: [333716] automated match to d1j8fa_ complexed with cna, zn |
Domain d5mara1: 5mar A:56-355 [331104] Other proteins in same PDB: d5mara2, d5marb2 automated match to d4rmha_ complexed with 7ke, act, ar6, dms, edo, gol, zn |
Domain d5marb1: 5mar B:56-355 [331084] Other proteins in same PDB: d5mara2, d5marb2 automated match to d4rmha_ complexed with 7ke, act, ar6, dms, edo, gol, zn |
Domain d5mata1: 5mat A:56-356 [329544] Other proteins in same PDB: d5mata2, d5matc2 automated match to d4rmha_ complexed with 7kj, p6g, pg4, so4, zn |
Domain d5matc1: 5mat C:56-356 [329582] Other proteins in same PDB: d5mata2, d5matc2 automated match to d4rmha_ complexed with 7kj, p6g, pg4, so4, zn |
Domain d5y0za_: 5y0z A: [355301] automated match to d1j8fc_ complexed with 8k9, zn |
Domain d5y0zb_: 5y0z B: [355266] automated match to d1j8fc_ complexed with 8k9, zn |
Domain d5y5na_: 5y5n A: [338859] automated match to d1j8fa_ complexed with 8no, zn |
Domain d5yqla1: 5yql A:56-356 [359075] Other proteins in same PDB: d5yqla2 automated match to d1j8fc_ complexed with a2i, bme, zn |
Domain d5yqma1: 5yqm A:56-356 [359056] Other proteins in same PDB: d5yqma2 automated match to d1j8fc_ complexed with a2x, bme, zn |
Domain d5yqna1: 5yqn A:56-356 [359081] Other proteins in same PDB: d5yqna2 automated match to d1j8fc_ complexed with l55, peg, zn |
Domain d5yqoa1: 5yqo A:56-356 [359050] Other proteins in same PDB: d5yqoa2 automated match to d1j8fc_ complexed with l5c, zn |
Domain d6l72a_: 6l72 A: [402165] automated match to d1j8fc_ complexed with omr, zn |
Domain d6nr0a_: 6nr0 A: [379338] automated match to d1j8fa_ complexed with gol, kxg, kxj, na, so4, zn |
Domain d6nr0b_: 6nr0 B: [379249] automated match to d1j8fa_ complexed with gol, kxg, kxj, na, so4, zn |
Domain d6qcna_: 6qcn A: [378650] automated match to d1j8fc_ complexed with ar6, que, zn |
Domain d6qcnb_: 6qcn B: [378651] automated match to d1j8fc_ complexed with ar6, que, zn |
Timeline for Protein Sirt2 histone deacetylase from c.31.1.5: Sir2 family of transcriptional regulators: