Lineage for Family a.4.5.31: DEP domain

  1. Root: SCOPe 2.05
  2. 1715731Class a: All alpha proteins [46456] (286 folds)
  3. 1720410Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 1721437Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families) (S)
    contains a small beta-sheet (wing)
  5. 1722310Family a.4.5.31: DEP domain [63483] (4 proteins)
    membrane-binding domain

Proteins:

  1. 1722311Pleckstrin [101039] (2 species)
    1. 1722312Species Human (Homo sapiens) [TaxId:9606] [116790] (2 PDB entries)
      Uniprot P08567 125-219 # structure of the N-terminal PH domain (1-105) is also known (50741)
    2. 1722315Species Mouse (Mus musculus) [TaxId:10090] [101040] (1 PDB entry)
  2. 1722317Pleckstrin 2 [101041] (1 species)
  3. 1722320Regulatory domain of epac2, domain 2 [81693] (1 species)
  4. 1722323Segment polarity protein Dishevelled-1 [63484] (1 species)

More info for Family a.4.5.31: DEP domain

Timeline for Family a.4.5.31: DEP domain: