SCOP 1.73: Family d.185.1.1: MPP-like

Lineage for Family d.185.1.1: MPP-like

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily)
   core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta

4. Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (2 families)
   Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues

5. Family d.185.1.1: MPP-like [63412] (6 proteins)
   Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal

Proteins:

1. Cytochrome bc1 core subunit 1 [63408] (3 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64304] (5 PDB entries)

   2. Species Chicken (Gallus gallus) [TaxId:9031] [55998] (3 PDB entries)

   3. Species Cow (Bos taurus) [TaxId:9913] [55997] (18 PDB entries)

2. Cytochrome bc1 core subunit 2 [63409] (3 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64305] (5 PDB entries)

   2. Species Chicken (Gallus gallus) [TaxId:9031] [56001] (9 PDB entries)

   3. Species Cow (Bos taurus) [TaxId:9913] [56000] (12 PDB entries)

3. Mitochondrial processing peptidase (MPP) alpha chain [64302] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64303] (4 PDB entries)

4. Mitochondrial processing peptidase (MPP) beta chain [64300] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64301] (4 PDB entries)

5. Presequence protease 1, PREP1 [143498] (1 species)
   duplication: comprises four domains of this fold; similar to the MPP alpha-beta heterodimer

   • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [143499] (1 PDB entry)

6. Protease III [143500] (1 species)
   duplication: comprises four domains of this fold

   • Species Escherichia coli [TaxId:562] [143501] (1 PDB entry)

More info for Family d.185.1.1: MPP-like

Timeline for Family d.185.1.1: MPP-like:

• Family d.185.1.1: MPP-like first appeared in SCOP 1.57
  
• Family d.185.1.1: MPP-like appears in SCOP 1.71
  
• Family d.185.1.1: MPP-like appears in SCOP 1.75
  
• Family d.185.1.1: MPP-like appears in the current release, SCOPe 2.08