SCOPe 2.08: Domain d1ii4h2: 1ii4 H:251-361

Lineage for d1ii4h2 (1ii4 H:251-361)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.4: I set domains [49159] (39 proteins)

6. Protein Fibroblast growth factor receptor, FGFR [49179] (4 species)

7. Species Human (Homo sapiens), FGFR2a [TaxId:9606] [49181] (11 PDB entries)

8. Domain d1ii4h2: 1ii4 H:251-361 [62411]
   Other proteins in same PDB: d1ii4a_, d1ii4b_, d1ii4c_, d1ii4d_
   mutant

Details for d1ii4h2

PDB Entry: 1ii4, 2.7 Å

PDB Description: crystal structure of ser252trp apert mutant fgf receptor 2 (fgfr2) in complex with fgf2

PDB Compounds: (H:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d1ii4h2:

Sequence, based on SEQRES records:

>d1ii4h2 b.1.1.4 (H:251-361) Fibroblast growth factor receptor, FGFR {Human (Homo sapiens), FGFR2a [TaxId: 9606]}
rwphrpilqaglpanastvvggdvefvckvysdaqphiqwikhvekngskygpdglpylk
vlkaagvnttdkeievlyirnvtfedageytclagnsigisfhsawltvlp

Sequence, based on observed residues (ATOM records):

>d1ii4h2 b.1.1.4 (H:251-361) Fibroblast growth factor receptor, FGFR {Human (Homo sapiens), FGFR2a [TaxId: 9606]}
rwphrpilqaglpanastvvggdvefvckvysdaqphiqwikhvpylkvlkaagvnttdk
eievlyirnvtfedageytclagnsigisfhsawltvlp

Timeline for d1ii4h2:

• d1ii4h2 first appeared in SCOP 1.57
  
• d1ii4h2 appears in SCOPe 2.07