SCOPe 2.08: Domain d1i4ta_: 1i4t A:

Lineage for d1i4ta_ (1i4t A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.238: BAR/IMD domain-like [116747] (1 superfamily)
   6 helices, homodimer of 3-helical domains

4. Superfamily a.238.1: BAR/IMD domain-like [103657] (5 families)
   core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends

5. Family a.238.1.2: Arfaptin, Rac-binding fragment [64599] (2 proteins)
   automatically mapped to Pfam PF06456

6. Protein Arfaptin, Rac-binding fragment [64600] (1 species)
   active form is a dimer

7. Species Human (Homo sapiens) [TaxId:9606] [64601] (4 PDB entries)

8. Domain d1i4ta_: 1i4t A: [61729]
   Other proteins in same PDB: d1i4td_
   complexed with gnp, mg

Details for d1i4ta_

PDB Entry: 1i4t, 2.6 Å

PDB Description: crystal structure analysis of rac1-gmppnp in complex with arfaptin

PDB Compounds: (A:) arfaptin 2

SCOPe Domain Sequences for d1i4ta_:

Sequence, based on SEQRES records:

>d1i4ta_ a.238.1.2 (A:) Arfaptin, Rac-binding fragment {Human (Homo sapiens) [TaxId: 9606]}
srtvdlelelqiellretkrkyesvlqlgraltahlysllqtqhalgdafadlsqkspel
qeefgynaetqkllckngetllgavnffvssintlvtktmedtlmtvkqyeaarleyday
rtdleelslgprdagtrgrlesaqatfqahrdkyeklrgdvaiklkfleenkikvmhkql
llfhnavsayfagnq

Sequence, based on observed residues (ATOM records):

>d1i4ta_ a.238.1.2 (A:) Arfaptin, Rac-binding fragment {Human (Homo sapiens) [TaxId: 9606]}
srtvdlelelqiellretkrkyesvlqlgraltahlysllqtqhalgdafadlsqkspel
qeefgynaetqkllckngetllgavnffvssintlvtktmedtlmtvkqyeaarleyday
rtdleelslgprdagrdkyeklrgdvaiklkfleenkikvmhkqlllfhnavsayfagnq

Timeline for d1i4ta_:

• d1i4ta_ first appeared in SCOP 1.57
  
• d1i4ta_ appears in SCOPe 2.07