SCOP 1.69: Domain d1hysc1: 1hys C:1-107

Lineage for d1hysc1 (1hys C:1-107)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (162 PDB entries)

8. Domain d1hysc1: 1hys C:1-107 [61420]
   Other proteins in same PDB: d1hysa1, d1hysa2, d1hysb_, d1hysc2, d1hysd1, d1hysd2
   part of Fab 28 against HIV-1 RT

Details for d1hysc1

PDB Entry: 1hys, 3 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase in complex with a polypurine tract rna:dna

SCOP Domain Sequences for d1hysc1:

Sequence; same for both SEQRES and ATOM records:

>d1hysc1 b.1.1.1 (C:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
diqmtqttsslsaslgdrvtiscsasqdissylnwyqqkpegtvklliyytsslhsgvps
afsgsgsgtdysltisnlepedfatyycqqyskfpwtfgggtkleik

Timeline for d1hysc1:

• d1hysc1 first appeared in SCOP 1.57
  
• d1hysc1 appears in SCOP 1.67
  
• d1hysc1 appears in SCOP 1.71
  
• d1hysc1 appears in the current release, SCOPe 2.08