SCOPe 2.07: Domain d1hr7g2: 1hr7 G:234-467

Lineage for d1hr7g2 (1hr7 G:234-467)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily)
   core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta

4. Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (3 families)
   Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues

5. Family d.185.1.1: MPP-like [63412] (7 proteins)
   Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal

6. Protein Mitochondrial processing peptidase (MPP) alpha chain [64302] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64303] (4 PDB entries)

8. Domain d1hr7g2: 1hr7 G:234-467 [61193]
   Other proteins in same PDB: d1hr7b1, d1hr7b2, d1hr7d1, d1hr7d2, d1hr7f1, d1hr7f2, d1hr7h1, d1hr7h2
   complexed with zn; mutant

Details for d1hr7g2

PDB Entry: 1hr7, 2.55 Å

PDB Description: yeast mitochondrial processing peptidase beta-e73q mutant

PDB Compounds: (G:) mitochondrial processing peptidase alpha subunit

SCOPe Domain Sequences for d1hr7g2:

Sequence, based on SEQRES records:

>d1hr7g2 d.185.1.1 (G:234-467) Mitochondrial processing peptidase (MPP) alpha chain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vaqytggescippapvfgnlpelfhiqigfeglpidhpdiyalatlqtllggggsfsagg
pgkgmysrlythvlnqyyfvencvafnhsysdsgifgislscipqaapqaveviaqqmyn
tfankdlrltedevsraknqlkssllmnlesklveledmgrqvlmhgrkipvnemiskie
dlkpddisrvaemiftgnvnnagngkgratvvmqgdrgsfgdvenvlkayglgn

Sequence, based on observed residues (ATOM records):

>d1hr7g2 d.185.1.1 (G:234-467) Mitochondrial processing peptidase (MPP) alpha chain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vaqytggescippapvfgnlpelfhiqigfeglpidhpdiyalatlqtllggggggpgkg
mysrlythvlnqyyfvencvafnhsysdsgifgislscipqaapqaveviaqqmyntfan
kdlrltedevsraknqlkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkp
ddisrvaemiftgnvnnagngkgratvvmqgdrgsfgdvenvlkayglgn

Timeline for d1hr7g2:

• d1hr7g2 first appeared in SCOP 1.57
  
• d1hr7g2 appears in SCOPe 2.06
  
• d1hr7g2 appears in the current release, SCOPe 2.08