SCOPe 2.02: Domain d1heza2: 1hez A:108-214

Lineage for d1heza2 (1hez A:108-214)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (134 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d1heza2: 1hez A:108-214 [60984]
   Other proteins in same PDB: d1heza1, d1hezb1, d1hezb2, d1hezc1, d1hezd1, d1hezd2, d1heze_
   part of IgM RF 2A2
   complexed with imd

Details for d1heza2

PDB Entry: 1hez, 2.7 Å

PDB Description: structure of p. magnus protein l bound to a human igm fab.

PDB Compounds: (A:) kappa light chain of ig

SCOPe Domain Sequences for d1heza2:

Sequence; same for both SEQRES and ATOM records:

>d1heza2 b.1.1.2 (A:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d1heza2:

• d1heza2 first appeared in SCOP 1.57
  
• d1heza2 appears in SCOPe 2.01
  
• d1heza2 appears in SCOPe 2.03
  
• d1heza2 appears in the current release, SCOPe 2.08