SCOP 1.75: Domain d1fn4b2: 1fn4 B:107-208

Lineage for d1fn4b2 (1fn4 B:107-208)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [88578] (5 PDB entries)

8. Domain d1fn4b2: 1fn4 B:107-208 [59887]
   Other proteins in same PDB: d1fn4a1, d1fn4a2, d1fn4b1, d1fn4c1, d1fn4c2, d1fn4d1
   part of Fab 198 against acetylcholine receptor

Details for d1fn4b2

PDB Entry: 1fn4, 2.8 Å

PDB Description: crystal structure of fab198, an efficient protector of acetylcholine receptor against myasthenogenic antibodies

PDB Compounds: (B:) monoclonal antibody against acetylcholine receptor

SCOP Domain Sequences for d1fn4b2:

Sequence; same for both SEQRES and ATOM records:

>d1fn4b2 b.1.1.2 (B:107-208) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Rat (Rattus norvegicus) [TaxId: 10116]}
tmvtvssvfplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgalssgvhtfpavlqsg
lytltssvtvpsstwssqavtcnvahpasstkvdkkivprdc

Timeline for d1fn4b2:

• d1fn4b2 first appeared in SCOP 1.57
  
• d1fn4b2 appears in SCOP 1.73
  
• d1fn4b2 appears in SCOPe 2.01
  
• d1fn4b2 appears in the current release, SCOPe 2.08