SCOPe 2.08: Domain d1f45a3: 1f45 A:212-306

Lineage for d1f45a3 (1f45 A:212-306)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.2: Fibronectin type III [49265] (2 families)

5. Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
   Pfam PF00041

6. Protein The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63673] (5 PDB entries)

8. Domain d1f45a3: 1f45 A:212-306 [59641]
   Other proteins in same PDB: d1f45a1, d1f45b_

Details for d1f45a3

PDB Entry: 1f45, 2.8 Å

PDB Description: human interleukin-12

PDB Compounds: (A:) interleukin-12 beta chain

SCOPe Domain Sequences for d1f45a3:

Sequence, based on SEQRES records:

>d1f45a3 b.1.2.1 (A:212-306) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
kpdppknlqlkplknsrqvevsweypdtwstphsyfsltfcvqvqgkskrekkdrvftdk
tsatvicrknasisvraqdryyssswsewasvpcs

Sequence, based on observed residues (ATOM records):

>d1f45a3 b.1.2.1 (A:212-306) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
kpdppknlqlkplknsrqvevsweypdtwstphsyfsltfcvqvqkdrvftdktsatvic
rsisvraqdryyssswsewasvpcs

Timeline for d1f45a3:

• d1f45a3 first appeared in SCOP 1.57
  
• d1f45a3 appears in SCOPe 2.07