SCOPe 2.03: Domain d1e4wl2: 1e4w L:108-214

Lineage for d1e4wl2 (1e4w L:108-214)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (364 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d1e4wl2: 1e4w L:108-214 [59235]
   Other proteins in same PDB: d1e4wh1, d1e4wh2, d1e4wl1
   part of anti-TGFalpha Fab TAB2
   complexed with cl, ni

Details for d1e4wl2

PDB Entry: 1e4w, 1.95 Å

PDB Description: crossreactive binding of a circularized peptide to an anti-tgfalpha antibody fab-fragment

PDB Compounds: (L:) tab2

SCOPe Domain Sequences for d1e4wl2:

Sequence; same for both SEQRES and ATOM records:

>d1e4wl2 b.1.1.2 (L:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvldswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d1e4wl2:

• d1e4wl2 first appeared in SCOP 1.57
  
• d1e4wl2 appears in SCOPe 2.02
  
• d1e4wl2 appears in SCOPe 2.04
  
• d1e4wl2 appears in the current release, SCOPe 2.08