Lineage for d1e4wl1 (1e4w L:1-107)

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 287095Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 287096Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 287097Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)
  6. 287738Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogeneous CDRs are listed as engineered species
  7. 288075Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (146 PDB entries)
  8. 288110Domain d1e4wl1: 1e4w L:1-107 [59234]
    Other proteins in same PDB: d1e4wh1, d1e4wh2, d1e4wl2
    part of anti-TGFalpha Fab TAB2
    complexed with cl, ni

Details for d1e4wl1

PDB Entry: 1e4w (more details), 1.95 Å

PDB Description: crossreactive binding of a circularized peptide to an anti-tgfalpha antibody fab-fragment

SCOP Domain Sequences for d1e4wl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1e4wl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
diqmtqtpsslsaslgdrvtiscrasqdishylnwfqqkpdgtvklliyytstlhsgvps
rfsgsgsgtdysltisnleeediafyfcqqggalpftfgsgtklaik

SCOP Domain Coordinates for d1e4wl1:

Click to download the PDB-style file with coordinates for d1e4wl1.
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Timeline for d1e4wl1:

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Domains from same chain:
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d1e4wl2