SCOPe 2.02: Superfamily g.44.1: RING/U-box

Lineage for Superfamily g.44.1: RING/U-box

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.44: RING/U-box [57849] (1 superfamily)
   dimetal(zinc)-bound alpha+beta motif; structurally diverse

4. Superfamily g.44.1: RING/U-box [57850] (7 families)

Families:

1. g.44.1.1: RING finger domain, C3HC4 [57851] (14 proteins)

2. g.44.1.2: U-box [90222] (5 proteins)
   Associated with multi-ubiquitination; lacks the RING-domain metal ion-binding residues

3. g.44.1.3: Variant RING domain [118300] (2 proteins)

4. g.44.1.4: IBR domain [144228] (1 protein)
   Smart 00647; RING-associated domain

5. g.44.1.5: Zf-UBP [161204] (3 proteins)
   Pfam PF02148

6. g.44.1.6: ZZ domain [161211] (3 proteins)
   Pfam PF00569

7. g.44.1.0: automated matches [191345] (1 protein)
   not a true family

More info for Superfamily g.44.1: RING/U-box

Timeline for Superfamily g.44.1: RING/U-box:

• Superfamily g.44.1: RING/U-box first appeared (with stable ids) in SCOP 1.55, called Superfamily g.44.1: RING finger domain, C3HC4
  
• Superfamily g.44.1: RING/U-box appears in SCOPe 2.01
  
• Superfamily g.44.1: RING/U-box appears in SCOPe 2.03
  
• Superfamily g.44.1: RING/U-box appears in the current release, SCOPe 2.08