Lineage for Family g.18.1.1: Complement control module/SCR domain

  1. Root: SCOPe 2.07
  2. 2581248Class g: Small proteins [56992] (98 folds)
  3. 2585277Fold g.18: Complement control module/SCR domain [57534] (1 superfamily)
    disulfide-rich all-beta fold
  4. 2585278Superfamily g.18.1: Complement control module/SCR domain [57535] (2 families) (S)
  5. 2585279Family g.18.1.1: Complement control module/SCR domain [57536] (15 proteins)
    Pfam PF00084

Proteins:

  1. 2585280beta2-glycoprotein I [57543] (1 species)
    consists of five modules with the C-terminal module fold being altered
  2. 2585299CD46 (membrane cofactor protein, MCP) [57541] (1 species)
  3. 2585317Complement C1R protease domains [75682] (1 species)
  4. 2585325Complement C1S protease domain [64566] (1 species)
  5. 2585328Complement control protein [57539] (1 species)
    • 2585329Species Vaccinia virus [TaxId:10245] [57540] (8 PDB entries)
      Uniprot P10998
      a complement protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
  6. 2585374Complement decay-accelerating factor (Daf, CD55) [90172] (1 species)
  7. 2585463Complement factor B [144115] (1 species)
    contains tandemrepeat of three SCR (Sushi) domains
  8. 2585468Complement receptor 1, cr1 [75680] (1 species)
  9. 2585475Complement receptor 2, cr2 [64564] (1 species)
  10. 2585487Factor H, 15th and 16th modules [57537] (1 species)
  11. 2585493GABA-B receptor 1 [118257] (1 species)
  12. 2585497Interleukin-15 receptor subunit alpha [161139] (2 species)
    1. 2585498Species Human (Homo sapiens) [TaxId:9606] [161141] (4 PDB entries)
      Uniprot Q13261 31-108! Uniprot Q13261 31-96
    2. 2585511Species Mouse (Mus musculus) [TaxId:10090] [161140] (1 PDB entry)
      Uniprot Q60819 35-103
  13. 2585514Interleukin-2 receptor alpha chain [144117] (1 species)
    consists of two segment-swapped SCR domains
  14. 2585528Mannan-binding lectin serine protease 2 (MASP-2) domains [111409] (1 species)
  15. 2585534automated matches [254612] (1 species)
    not a true protein

More info for Family g.18.1.1: Complement control module/SCR domain

Timeline for Family g.18.1.1: Complement control module/SCR domain: