Lineage for Family g.17.1.2: Transforming growth factor (TGF)-beta

  1. Root: SCOPe 2.07
  2. 2581248Class g: Small proteins [56992] (98 folds)
  3. 2584898Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2584899Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2584990Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 protein domains)

Protein Domains:

  1. 2584991Activin A (Inhibin beta A) [90170] (1 species)
  2. 2585010Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)
  3. 2585035Bone morphogenetic protein-7 (BMP-7) [57514] (1 species)
  4. 2585041Glial cell-derived neurotrophic factor, GDNF [57518] (1 species)
  5. 2585047TGF-beta1 [57512] (1 species)
  6. 2585063TGF-beta2 [57510] (2 species)
    1. 2585064Species Human (Homo sapiens) [TaxId:9606] [57511] (4 PDB entries)
    2. 2585072Species Mouse (Mus musculus) [TaxId:10090] [330451] (2 PDB entries)
  7. 2585078TGF-beta3 [57508] (1 species)
  8. 2585088automated matches [190307] (1 species)
    not a true protein

More info for Family g.17.1.2: Transforming growth factor (TGF)-beta

Timeline for Family g.17.1.2: Transforming growth factor (TGF)-beta: