SCOP 1.75: Family g.68.1.1: Ovomucoid domain III-like

Lineage for Family g.68.1.1: Ovomucoid domain III-like

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.68: Kazal-type serine protease inhibitors [100894] (1 superfamily)

4. Superfamily g.68.1: Kazal-type serine protease inhibitors [100895] (2 families)
   conserved core consists of a helix and a loop crosslinked with two disulfides

5. Family g.68.1.1: Ovomucoid domain III-like [57468] (10 proteins)

Proteins:

1. Ascidian trypsin inhibitor [75678] (1 species)

   • Species Sea squirt (Halocynthia roretzi) [TaxId:7729] [75679] (1 PDB entry)

2. Blood-sucking insect-derived tryptase inhibitor [57476] (2 species)
   duplication: contains two domains of this fold

   1. Species Bug (Rhodnius prolixus), rhodniin [TaxId:13249] [57477] (2 PDB entries)

   2. Species Triatoma infestans [TaxId:30076] [161138] (2 PDB entries)
      Uniprot Q95P16 170-222! Uniprot Q95P16 5-50
      infestin

3. Dipetalin [75676] (1 species)

   • Species Dipetalogaster maximus, dipetalin [TaxId:72496] [75677] (1 PDB entry)

4. Domain of BM-40/SPARC/osteonectin [57478] (1 species)
   the C-terminal part of FS module

   • Species Human (Homo sapiens) [TaxId:9606] [57479] (2 PDB entries)

5. Domain of follistatin [90166] (1 species)
   the C-terminal part of the heparin-binding module, FS1

   • Species Rat (Rattus norvegicus) [TaxId:10116] [90167] (3 PDB entries)

6. Leech derived tryptase inhibitor (LDTI-C) [57484] (1 species)

   • Species Medicinal leech (Hirudo medicinalis) [TaxId:6421] [57485] (2 PDB entries)

7. Ovomucoid domains [57469] (3 species)
   unless specified in the comment, the listed structures are of domain III

   1. Species Japanese quail (Coturnix coturnix japonica) [TaxId:93934] [57471] (2 PDB entries)

   2. Species Silver pheasant (Lophura nycthemera) [TaxId:9046] [57472] (4 PDB entries)

   3. Species Turkey (Meleagris gallopavo) [TaxId:9103] [57470] (38 PDB entries)

8. PEC-60 peptide [57482] (1 species)

   • Species Pig (Sus scrofa) [TaxId:9823] [57483] (1 PDB entry)

9. Secretory trypsin inhibitor [57473] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [57474] (3 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [57475] (1 PDB entry)

10. Seminal plasma inhibitor IIa [57480] (1 species)

    • Species Cow (Bos taurus) [TaxId:9913] [57481] (2 PDB entries)

More info for Family g.68.1.1: Ovomucoid domain III-like

Timeline for Family g.68.1.1: Ovomucoid domain III-like:

• Family g.68.1.1: Ovomucoid domain III-like first appeared (with stable ids) in SCOP 1.55, called Family g.15.1.1: Animal Kazal-type inhibitors
  
• Family g.68.1.1: Ovomucoid domain III-like appears in SCOP 1.73
  
• Family g.68.1.1: Ovomucoid domain III-like appears in SCOPe 2.01
  
• Family g.68.1.1: Ovomucoid domain III-like appears in the current release, SCOPe 2.08