SCOPe 2.07: Fold f.4: Transmembrane beta-barrels

Lineage for Fold f.4: Transmembrane beta-barrels

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.4: Transmembrane beta-barrels [56924] (7 superfamilies)
   not a true fold, gathers together transmembrane barrels of different (n,S)

Superfamilies:

1. f.4.1: OMPA-like [56925] (5 families)
   forms (8,10) barrel

2. f.4.2: Outer membrane phospholipase A (OMPLA) [56931] (1 family)
   forms (12,16) barrel

3. f.4.3: Porins [56935] (5 families)

4. f.4.4: OMPT-like [69917] (3 families)
   forms (10,12) barrel

5. f.4.5: Autotransporter [103515] (1 family)
   forms (12,14) barrel; contains a long alpha-helix running along the barrel axis
   automatically mapped to Pfam PF03797

6. f.4.6: Tsx-like channel [111364] (1 family)
   forms (12,16) barrel
   automatically mapped to Pfam PF03502

7. f.4.7: Outer membrane carboxylate (Occ) channels [310584] (3 families)
   Pfam PF03573; Phylogeny discussed in PubMed 22272184
   labile trimers according to PubMed 17952093; each subunit forms (18,22) barrel

More info for Fold f.4: Transmembrane beta-barrels

Timeline for Fold f.4: Transmembrane beta-barrels:

• Fold f.4: Transmembrane beta-barrels first appeared (with stable ids) in SCOP 1.55
  
• Fold f.4: Transmembrane beta-barrels appears in SCOPe 2.06
  
• Fold f.4: Transmembrane beta-barrels appears in the current release, SCOPe 2.08