Lineage for Superfamily c.108.1: HAD-like

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 847927Fold c.108: HAD-like [56783] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456
  4. 847928Superfamily c.108.1: HAD-like [56784] (25 families) (S)
    usually contains an insertion (sub)domain after strand 1

Families:

  1. 847929c.108.1.1: HAD-related [56785] (2 proteins)
    the insertion subdomain is a 4-helical bundle
  2. 847948c.108.1.2: YihX-like [56789] (2 proteins)
    the insertion subdomain is a 4-helical bundle
  3. 847969c.108.1.3: Phosphonoacetaldehyde hydrolase-like [56792] (2 proteins)
    the insertion subdomain is a 4-helical bundle
  4. 847993c.108.1.4: Phosphoserine phosphatase [64511] (1 protein)
    the insertion subdomain is a 4-helical bundle
  5. 848015c.108.1.5: Probable phosphatase YrbI [69467] (1 protein)
    the insertion subdomain is a beta-hairpin involved into tetramerisation
  6. 848034c.108.1.6: beta-Phosphoglucomutase-like [75173] (9 proteins)
    the insertion subdomain is a 4-helical bundle
  7. 848075c.108.1.7: Meta-cation ATPase, catalytic domain P [81656] (2 proteins)
    interrupted by a large insertion, domain N
  8. 848105c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2) [82382] (1 protein)
    the insertion subdomain is a 4-helical bundle; dephosphorylates dUMP and dTMP
  9. 848120c.108.1.9: phosphatase domain of polynucleotide kinase [82385] (2 proteins)
    no insertion subdomains
  10. 848143c.108.1.10: Predicted hydrolases Cof [82388] (11 proteins)
    contains an alpha+beta subdomain inserted into a new site after strand 3
  11. 848216c.108.1.11: Homoserine kinase ThrH [102304] (1 protein)
    the insertion subdomain is a rudiment 4-helical bundle
  12. 848223c.108.1.12: Class B acid phosphatase, AphA [102307] (1 protein)
    the insertion subdomain is a helical hairpin
  13. 848260c.108.1.13: Hypothetical protein MW1667 (SA1546) [102310] (1 protein)
    the insertion subdomain is multi-helical
  14. 848264c.108.1.14: NagD-like [102317] (6 proteins)
    duplication: consists of two segment-swapped domains of this fold; this results in the insertion of a circularly permuted domain after strand 3, analogously to the Cof family
  15. 848288c.108.1.15: Trehalose-phosphatase [110506] (1 protein)
    Pfam PF02358; contains an insert alpha+beta subdomain; similar overall fold to the Cof family
  16. 848292c.108.1.16: NLI interacting factor-like phosphatase [110509] (1 protein)
    Pfam PF03031; NIF; the insertion subdomain is a 3-stranded beta-sheet;
  17. 848297c.108.1.17: Magnesium-dependent phosphatase-1, Mdp1 [117509] (1 protein)
    the insertion subdomain is a 3-stranded beta-sheet different from the NIF family
  18. 848305c.108.1.18: Hypothetical protein VC0232 [117512] (1 protein)
    contains a deletion in the common fold; segment-swapped tetramer
  19. 848312c.108.1.19: Histidinol phosphatase-like [142177] (3 proteins)
    no insertion subdomains
  20. 848334c.108.1.20: MtnX-like [142180] (1 protein)
    Pfam PF06888; the insertion subdomain is a rudiment 4-helical bundle
  21. 848339c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) [142183] (1 protein)
    Pfam PF05822; the insertion subdomain is a rudiment 4-helical bundle
  22. 848346c.108.1.22: Enolase-phosphatase E1 [142186] (2 proteins)
    the insertion subdomain is a 4-helical bundle
  23. 848357c.108.1.23: 5' nucleotidase-like [142191] (1 protein)
    Pfam PF05761; the insertion domain cosists of 3-helical bundle and a pseudo beta-barrel; contains extra C-terminal long alpha hairpin subdomain ((46556))
  24. 848361c.108.1.24: AF1437-like [159537] (1 protein)
    the insertion subdomain is a rudiment 4-helical bundle; extra alpha-hairpin insertion after strand 3
  25. 848365c.108.1.25: BT0820-like [159540] (1 protein)
    PfamB PB073209; deletion in the common fold; segment-swapped dimer

More info for Superfamily c.108.1: HAD-like

Timeline for Superfamily c.108.1: HAD-like: