Lineage for Family e.8.1.4: RNA-dependent RNA-polymerase

  1. Root: SCOPe 2.06
  2. 2217451Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)
  3. 2220074Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2220075Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2220913Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 protein domains)

Protein Domains:

  1. 2220914Reovirus polymerase lambda3 [82841] (1 species)
    contains additional N-terminal domain (res. 1-380) and C-terminal "bracelet" domain (res. 891-1267)
  2. 2220921Viral RNA polymerase [56695] (18 species)
    1. 2220922Species Avian infectious bursal disease virus [TaxId:10995] [160955] (1 PDB entry)
      Uniprot Q9Q6Q5 31-804
    2. 2220924Species Bovine viral diarrhea virus [TaxId:11099] [103401] (3 PDB entries)
    3. 2220931Species Foot-and-mouth disease virus - type c [TaxId:12116] [187085] (9 PDB entries)
    4. 2220941Species Foot-and-mouth disease virus [TaxId:12110] [111302] (7 PDB entries)
      Uniprot Q9QCE4 1858-2327
    5. 2220951Species Hepatitis C virus isolate bk [TaxId:11105] [195056] (4 PDB entries)
    6. 2220960Species Hepatitis c virus isolate [TaxId:420174] [188905] (22 PDB entries)
    7. 2221003Species Hepatitis c virus subtype 1a [TaxId:31646] [189928] (4 PDB entries)
    8. 2221010Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries)
    9. 2221147Species Hepatitis C virus [TaxId:356411] [193797] (2 PDB entries)
    10. 2221150Species Human poliovirus 1 [TaxId:12081] [256393] (8 PDB entries)
    11. 2221159Species Human rhinovirus 14, HRV-14 [TaxId:12131] [111301] (2 PDB entries)
      Uniprot P03303 1720-2179
    12. 2221162Species Human rhinovirus 16 [TaxId:31708] [188024] (2 PDB entries)
    13. 2221170Species Human rhinovirus 16, HRV-16 [TaxId:31708] [111300] (2 PDB entries)
      Uniprot Q82122 1694-2153
    14. 2221175Species Human rhinovirus 1B, HRV-1B [TaxId:12129] [111299] (2 PDB entries)
      Uniprot P12916 1698-2157
    15. 2221178Species Norwalk virus [TaxId:11983] [103400] (8 PDB entries)
    16. 2221189Species Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (12 PDB entries)
      Uniprot P03300 1748-2208
    17. 2221221Species Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)
    18. 2288058Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] [331359] (1 PDB entry)
  3. 2221226automated matches [190260] (29 species)
    not a true protein
    1. 2221227Species Bovine viral diarrhea virus [TaxId:11099] [255087] (1 PDB entry)
    2. 2221229Species Coxsackievirus b3 [TaxId:103903] [188493] (5 PDB entries)
    3. 2221235Species Coxsackievirus b3 [TaxId:12072] [271111] (10 PDB entries)
    4. 2221238Species Foot-and-mouth disease virus [TaxId:12120] [272422] (2 PDB entries)
    5. 2221241Species Hepatitis B virus [TaxId:10407] [259720] (1 PDB entry)
    6. 2221243Species Hepatitis c virus (isolate 1) [TaxId:11104] [261697] (1 PDB entry)
    7. 2221245Species Hepatitis C virus isolate bk [TaxId:11105] [188687] (11 PDB entries)
    8. 2221268Species Hepatitis c virus isolate hc-j6 [TaxId:11113] [189608] (1 PDB entry)
    9. 2221270Species Hepatitis c virus isolate hc-j8 [TaxId:11115] [188981] (2 PDB entries)
    10. 2221275Species Hepatitis c virus isolate [TaxId:420174] [188851] (1 PDB entry)
    11. 2221278Species Hepatitis c virus jfh-1 [TaxId:356411] [189047] (3 PDB entries)
    12. 2221285Species Hepatitis c virus subtype 1a [TaxId:31646] [189338] (1 PDB entry)
    13. 2221289Species Hepatitis c virus subtype 1b [TaxId:31647] [187148] (4 PDB entries)
    14. 2221298Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)
    15. 2221383Species Hepatitis C virus [TaxId:11105] [188793] (3 PDB entries)
    16. 2221389Species Hepatitis C virus [TaxId:333284] [188792] (1 PDB entry)
    17. 2221391Species Hepatitis C virus [TaxId:356411] [189609] (1 PDB entry)
    18. 2221393Species Hepatitis C virus [TaxId:420174] [189885] (4 PDB entries)
    19. 2221401Species Human coxsackievirus B3 [TaxId:12072] [193138] (3 PDB entries)
    20. 2221414Species Human coxsackievirus [TaxId:12072] [188608] (1 PDB entry)
    21. 2221416Species Human enterovirus 71 [TaxId:39054] [189988] (4 PDB entries)
    22. 2221421Species Human poliovirus 1 [TaxId:12081] [193135] (16 PDB entries)
    23. 2221443Species Human rhinovirus a16 [TaxId:31708] [193142] (1 PDB entry)
    24. 2221445Species Murine norovirus 1 [TaxId:223997] [189982] (8 PDB entries)
    25. 2221473Species Murine norovirus [TaxId:223997] [226374] (2 PDB entries)
    26. 2221480Species Norwalk-like virus [TaxId:95340] [260334] (1 PDB entry)
    27. 2288056Species Hepatitis c virus genotype 1b (isolate con1) [TaxId:333284] [331357] (7 PDB entries)
    28. 2293070Species Enterovirus d68 [TaxId:42789] [336371] (1 PDB entry)
    29. 2294678Species Hepatitis c virus genotype 1b (isolate bk) [TaxId:11105] [337979] (1 PDB entry)

More info for Family e.8.1.4: RNA-dependent RNA-polymerase

Timeline for Family e.8.1.4: RNA-dependent RNA-polymerase: