Lineage for Family e.8.1.4: RNA-dependent RNA-polymerase

  1. Root: SCOPe 2.07
  2. 2568173Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2571153Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2571154Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2572036Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 protein domains)

Protein Domains:

  1. 2572037Reovirus polymerase lambda3 [82841] (1 species)
    contains additional N-terminal domain (res. 1-380) and C-terminal "bracelet" domain (res. 891-1267)
  2. 2572044Viral RNA polymerase [56695] (17 species)
    1. 2572045Species Avian infectious bursal disease virus [TaxId:10995] [160955] (1 PDB entry)
      Uniprot Q9Q6Q5 31-804
    2. 2572047Species Bovine viral diarrhea virus [TaxId:11099] [103401] (3 PDB entries)
    3. 2572054Species Foot-and-mouth disease virus - type c [TaxId:12116] [187085] (9 PDB entries)
    4. 2572064Species Foot-and-mouth disease virus [TaxId:12110] [111302] (7 PDB entries)
      Uniprot Q9QCE4 1858-2327
    5. 2572074Species Hepatitis C virus genotype 1b (isolate bk) [TaxId:11105] [195056] (4 PDB entries)
    6. 2572083Species Hepatitis C virus genotype 2a (isolate jfh-1) [TaxId:356411] [193797] (3 PDB entries)
    7. 2572087Species Hepatitis C virus subtype 1a [TaxId:31646] [189928] (4 PDB entries)
    8. 2572094Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries)
    9. 2572231Species Hepatitis C virus [TaxId:420174] [188905] (22 PDB entries)
    10. 2572274Species Human poliovirus 1 [TaxId:12081] [256393] (8 PDB entries)
    11. 2572283Species Human rhinovirus 14, HRV-14 [TaxId:12131] [111301] (2 PDB entries)
      Uniprot P03303 1720-2179
    12. 2572286Species Human rhinovirus 16 [TaxId:31708] [188024] (2 PDB entries)
    13. 2572294Species Human rhinovirus 16, HRV-16 [TaxId:31708] [111300] (2 PDB entries)
      Uniprot Q82122 1694-2153
    14. 2572299Species Human rhinovirus 1B, HRV-1B [TaxId:12129] [111299] (2 PDB entries)
      Uniprot P12916 1698-2157
    15. 2572302Species Norwalk virus [TaxId:11983] [103400] (8 PDB entries)
    16. 2572313Species Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (12 PDB entries)
      Uniprot P03300 1748-2208
    17. 2572345Species Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)
  3. 2572350automated matches [190260] (24 species)
    not a true protein
    1. 2572351Species Bovine viral diarrhea virus [TaxId:11099] [255087] (1 PDB entry)
    2. 2572353Species Coxsackievirus b3 [TaxId:103903] [188493] (5 PDB entries)
    3. 2572359Species Coxsackievirus b3 [TaxId:12072] [271111] (10 PDB entries)
    4. 2572370Species Enterovirus d68 [TaxId:42789] [336371] (1 PDB entry)
    5. 2572372Species Foot-and-mouth disease virus [TaxId:12120] [272422] (2 PDB entries)
    6. 2572375Species Hepatitis B virus [TaxId:10407] [259720] (1 PDB entry)
    7. 2572377Species Hepatitis C virus (isolate 1) [TaxId:11104] [261697] (1 PDB entry)
    8. 2572379Species Hepatitis C virus genotype 1b (isolate bk) [TaxId:11105] [188687] (15 PDB entries)
    9. 2572409Species Hepatitis C virus genotype 1b (isolate con1) [TaxId:333284] [188792] (8 PDB entries)
    10. 2572425Species Hepatitis C virus genotype 2a (isolate jfh-1) [TaxId:356411] [189047] (4 PDB entries)
    11. 2572433Species Hepatitis C virus isolate hc-j6 [TaxId:11113] [189608] (1 PDB entry)
    12. 2572435Species Hepatitis C virus isolate hc-j8 [TaxId:11115] [188981] (2 PDB entries)
    13. 2572440Species Hepatitis C virus subtype 1a [TaxId:31646] [189338] (1 PDB entry)
    14. 2572444Species Hepatitis C virus subtype 1b [TaxId:31647] [187148] (4 PDB entries)
    15. 2572455Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)
    16. 2572548Species Hepatitis C virus [TaxId:420174] [189885] (5 PDB entries)
    17. 2572558Species Human coxsackievirus B3 [TaxId:12072] [193138] (3 PDB entries)
    18. 2572571Species Human coxsackievirus [TaxId:12072] [188608] (1 PDB entry)
    19. 2572573Species Human enterovirus 71 [TaxId:39054] [189988] (4 PDB entries)
    20. 2572578Species Human poliovirus 1 [TaxId:12081] [193135] (16 PDB entries)
    21. 2572600Species Human rhinovirus a16 [TaxId:31708] [193142] (1 PDB entry)
    22. 2572602Species Murine norovirus 1 [TaxId:223997] [189982] (8 PDB entries)
    23. 2572630Species Murine norovirus [TaxId:223997] [226374] (2 PDB entries)
    24. 2572637Species Norwalk-like virus [TaxId:95340] [260334] (1 PDB entry)

More info for Family e.8.1.4: RNA-dependent RNA-polymerase

Timeline for Family e.8.1.4: RNA-dependent RNA-polymerase: