Lineage for Family e.8.1.2: Reverse transcriptase

  1. Root: SCOPe 2.05
  2. 1949014Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)
  3. 1951566Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 1951567Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 1951913Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

Proteins:

  1. 1951914HIV-1 reverse transcriptase [56689] (3 species)
    1. 1951915Species Hiv-1 m:b_hxb2r [TaxId:11706] [190022] (22 PDB entries)
    2. 1951956Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (153 PDB entries)
      Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
    3. 1952256Species Human immunodeficiency virus type 2 [TaxId:11709] [82840] (1 PDB entry)
  2. 1952259MMLV reverse transcriptase [56687] (1 species)
  3. 1952286automated matches [190211] (5 species)
    not a true protein
    1. 1952287Species Hiv-1 m:b_hxb2r [TaxId:11706] [187165] (10 PDB entries)
    2. 1952306Species Human immunodeficiency virus 1 [TaxId:11676] [186967] (7 PDB entries)
    3. 1952317Species Human immunodeficiency virus type 1 bh10 [TaxId:11678] [225820] (18 PDB entries)
    4. 1952342Species Human immunodeficiency virus type 1 [TaxId:11678] [226272] (12 PDB entries)
    5. 1952364Species Moloney murine leukemia virus [TaxId:11801] [188900] (1 PDB entry)

More info for Family e.8.1.2: Reverse transcriptase

Timeline for Family e.8.1.2: Reverse transcriptase: