Lineage for Family e.8.1.1: DNA polymerase I

  1. Root: SCOP 1.75
  2. 883176Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)
  3. 884269Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 884270Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 884271Family e.8.1.1: DNA polymerase I [56673] (4 proteins)

Proteins:

  1. 884272DNA polymerase I (Klenow fragment) [56674] (3 species)
    1. 884273Species Bacillus stearothermophilus, newly identified strain as yet unnamed [TaxId:1422] [56677] (42 PDB entries)
      Uniprot Q5KWC1 299-878 # 99% sequence identity; Geobacillus kaustophilus TaxID:1462
      Uniprot Q45458 298-876 # 88% sequence identity
    2. 884320Species Escherichia coli [TaxId:562] [56675] (14 PDB entries)
    3. 884335Species Thermus aquaticus [TaxId:271] [56676] (13 PDB entries)
  2. 884349Family B DNA polymerase [56680] (7 species)
    1. 884350Species Archaeon Desulfurococcus tok [TaxId:108142] [56684] (2 PDB entries)
    2. 884353Species Archaeon Pyrococcus kodakaraensis [TaxId:311400] [56685] (2 PDB entries)
      Uniprot P56689 1-758 # 93% sequence identity; Thermococcus kodakarensis KOD1 TaxID: 69014
    3. 884356Species Archaeon Thermococcus gorgonarius [TaxId:71997] [56682] (3 PDB entries)
    4. 884360Species Archaeon Thermococcus sp., 9on-7 [TaxId:35749] [56683] (1 PDB entry)
    5. 884362Species Bacteriophage RB69 [TaxId:12353] [56681] (15 PDB entries)
    6. 884394Species Escherichia coli [TaxId:562] [103399] (1 PDB entry)
    7. 884396Species Sulfolobus solfataricus [TaxId:2287] [118192] (1 PDB entry)
      Uniprot P26811 40-864
  3. 884398phi29 DNA polymerase [118193] (1 species)
  4. 884418T7 phage DNA polymerase [56678] (1 species)

More info for Family e.8.1.1: DNA polymerase I

Timeline for Family e.8.1.1: DNA polymerase I: