Lineage for Protein: beta-Lactamase, class A

  1. Root: SCOPe 2.04
  2. 1689992Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)
  3. 1690252Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
    contains a cluster of helices and an alpha+beta sandwich
  4. 1690253Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families) (S)
  5. 1690254Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)
  6. 1690477Protein beta-Lactamase, class A [56606] (16 species)

Species:

  1. 1690478Bacillus licheniformis [TaxId:1402] [56612] (11 PDB entries)
    1. Domains for 1i2s:
      1. 1690479Domain d1i2sa_: 1i2s A: [71104]
        complexed with cit, na
      2. 1690480Domain d1i2sb_: 1i2s B: [71105]
        complexed with cit, na
    2. Domains for 1i2w:
      1. 1690481Domain d1i2wa_: 1i2w A: [71106]
        complexed with cfx, out
      2. 1690482Domain d1i2wb_: 1i2w B: [71107]
        complexed with cfx, out
    3. Domains for 1mbl:
      1. 1690491Domain d1mbla_: 1mbl A: [42723]
        complexed with so4; mutant
      2. 1690492Domain d1mblb_: 1mbl B: [42724]
        complexed with so4; mutant
    4. Domains for 2blm:
      1. 1690495Domain d2blma_: 2blm A: [42725]
        CA-atoms only
      2. 1690496Domain d2blmb_: 2blm B: [42726]
        CA-atoms only
    5. Domain for 3ly3:
    6. Domain for 3ly4:
    7. Domains for 3m2j:
      1. 1690484Domain d3m2ja_: 3m2j A: [180745]
        automated match to d1mbla_
        complexed with f5m, so4
      2. 1690485Domain d3m2jb_: 3m2j B: [180746]
        automated match to d1mbla_
        complexed with f5m, so4
    8. Domains for 3sh7:
      1. 1690497Domain d3sh7a_: 3sh7 A: [197443]
        automated match to d3ly3a_
        complexed with bb0
      2. 1690498Domain d3sh7b_: 3sh7 B: [193681]
        automated match to d3ly3a_
        complexed with bb0
    9. Domains for 3sh8:
      1. 1690493Domain d3sh8a_: 3sh8 A: [185375]
        automated match to d2blma_
        complexed with ced
      2. 1690494Domain d3sh8b_: 3sh8 B: [185376]
        automated match to d2blma_
        complexed with ced
    10. Domains for 3sh9:
      1. 1690486Domain d3sh9a_: 3sh9 A: [216414]
        automated match to d3sh8a_
        complexed with bb0, pcz
      2. 1690487Domain d3sh9b_: 3sh9 B: [216415]
        automated match to d3sh8a_
        complexed with bb0, pcz
    11. Domains for 4blm:
      1. 1690488Domain d4blma_: 4blm A: [42721]
        complexed with so4
      2. 1690489Domain d4blmb_: 4blm B: [42722]
        complexed with so4
  2. 1690499Enterobacter cloacae, NMC-A carbapenemase [TaxId:550] [56613] (2 PDB entries)
    1. Domain for 1bue:
    2. Domain for 1bul:
  3. 1690502Escherichia coli, TEM-1 [TaxId:562] [56607] (37 PDB entries)
    1. Domain for 1axb:
    2. Domain for 1bt5:
    3. Domain for 1btl:
    4. Domain for 1ck3:
    5. Domain for 1erm:
    6. Domain for 1ero:
    7. Domain for 1erq:
    8. Domain for 1esu:
    9. Domain for 1fqg:
    10. Domain for 1jtd:
    11. Domains for 1jtg:
      1. 1690517Domain d1jtga_: 1jtg A: [67266]
        Other proteins in same PDB: d1jtgb_, d1jtgd_
        complexed with ca
      2. 1690518Domain d1jtgc_: 1jtg C: [67268]
        Other proteins in same PDB: d1jtgb_, d1jtgd_
        complexed with ca
    12. Domain for 1jvj:
    13. Domain for 1jwp:
    14. Domain for 1jwv:
    15. Domain for 1jwz:
    16. Domain for 1lhy:
    17. Domain for 1li0:
    18. Domain for 1li9:
    19. Domain for 1m40:
      • 1690503Domain d1m40a_: 1m40 A: [74437]
        ultra high resolution structure
        complexed with cb4, k, po4
    20. Domain for 1nxy:
    21. Domain for 1ny0:
    22. Domain for 1nym:
    23. Domain for 1nyy:
    24. Domain for 1pzo:
    25. Domain for 1pzp:
    26. Domains for 1s0w:
      1. 1690540Domain d1s0wa_: 1s0w A: [98309]
        Other proteins in same PDB: d1s0wc_, d1s0wd_
        complexed with ca
      2. 1690541Domain d1s0wb_: 1s0w B: [98310]
        Other proteins in same PDB: d1s0wc_, d1s0wd_
        complexed with ca
    27. Domain for 1tem:
    28. Domain for 1xpb:
    29. Domains for 1xxm:
      1. 1690534Domain d1xxma_: 1xxm A: [162118]
        Other proteins in same PDB: d1xxmc_, d1xxmd_
        automated match to d1axba_
        complexed with ca
      2. 1690535Domain d1xxmb_: 1xxm B: [162119]
        Other proteins in same PDB: d1xxmc_, d1xxmd_
        automated match to d1axba_
        complexed with ca
    30. Domain for 1yt4:
    31. Domain for 1zg4:
    32. Domain for 1zg6:
    33. Domains for 2b5r:
      1. 1690513Domain d2b5ra1: 2b5r A:26-288 [144952]
        Other proteins in same PDB: d2b5rc_, d2b5rd_
      2. 1690514Domain d2b5rb_: 2b5r B: [144953]
        Other proteins in same PDB: d2b5rc_, d2b5rd_
        automated match to d2b5ra1
    34. Domain for 3cmz:
    35. Domain for 4gku:
    36. Domains for 4ibx:
      1. 1690543Domain d4ibxa_: 4ibx A: [202603]
        automated match to d4ibxb_
        complexed with ca, mes, so4
      2. 1690544Domain d4ibxb_: 4ibx B: [196860]
        automated match to d1zg4a1
        complexed with ca, mes, so4
      3. 1690545Domain d4ibxc_: 4ibx C: [202604]
        automated match to d4ibxb_
        complexed with ca, mes, so4
      4. 1690546Domain d4ibxd_: 4ibx D: [202605]
        automated match to d4ibxb_
        complexed with ca, mes, so4
      5. 1690547Domain d4ibxe_: 4ibx E: [202606]
        automated match to d4ibxb_
        complexed with ca, mes, so4
    37. Domain for 4mez:
  4. 1690548Escherichia coli, TOHO-1 [TaxId:562] [56608] (18 PDB entries)
    1. Domain for 1bza:
    2. Domain for 1iyo:
    3. Domain for 1iyp:
    4. Domain for 1iyq:
    5. Domain for 1iys:
    6. Domain for 1we4:
    7. Domain for 2wyx:
    8. Domain for 2xqz:
    9. Domain for 2xr0:
    10. Domain for 2zq7:
    11. Domain for 2zq8:
    12. Domain for 2zq9:
    13. Domain for 2zqa:
    14. Domain for 2zqc:
    15. Domain for 2zqd:
    16. Domain for 4bd0:
    17. Domain for 4bd1:
    18. Domain for 4c3q:
  5. 1690567Klebsiella pneumoniae [TaxId:573] [225597] (9 PDB entries)
    1. Domain for 3d4f:
    2. Domain for 3oph:
    3. Domain for 3opl:
    4. Domain for 3opp:
    5. Domain for 3opr:
    6. Domain for 4gd6:
    7. Domain for 4gd8:
    8. Domain for 4gdb:
    9. Domain for 4jpm:
  6. 1690577Klebsiella pneumoniae, SHV-1 [TaxId:573] [56609] (23 PDB entries)
    inhibited by tazobactam
    Uniprot Q5PSW7 ! Uniprot P14557 22-286
    1. Domain for 1ong:
    2. Domain for 1q2p:
    3. Domain for 1rcj:
    4. Domain for 1shv:
    5. Domain for 1tdg:
    6. Domain for 1tdl:
    7. Domain for 1vm1:
    8. Domain for 2a3u:
    9. Domain for 2a49:
    10. Domain for 2g2w:
    11. Domain for 2h0t:
    12. Domain for 2h0y:
    13. Domain for 2h10:
    14. Domain for 3n4i:
    15. Domain for 3v50:
    16. Domain for 3v5m:
    17. Domain for 4fcf:
    18. Domain for 4fd8:
    19. Domain for 4fh2:
    20. Domain for 4fh4:
    21. Domain for 4mbf:
    22. Domain for 4mbh:
    23. Domain for 4mbk:
  7. 1690601Klebsiella pneumoniae, SHV-2 [TaxId:573] [90082] (10 PDB entries)
    almost identical sequence to SHV-1
    1. Domain for 1n9b:
    2. Domain for 2g2u:
    3. Domain for 2h5s:
    4. Domain for 2zd8:
    5. Domain for 3c4o:
    6. Domain for 3c4p:
    7. Domain for 3mke:
    8. Domain for 3mkf:
    9. Domain for 3mxr:
    10. Domain for 3mxs:
  8. 1690612Klebsiella pneumoniae, TEM52 [TaxId:573] [64473] (1 PDB entry)
  9. 1690619Mycobacterium fortuitum [TaxId:1766] [56615] (1 PDB entry)
  10. 1690621Proteus vulgaris [TaxId:585] [75596] (1 PDB entry)
  11. 1690624Pseudomonas aeruginosa, PER-1 [TaxId:287] [56616] (1 PDB entry)
  12. 1690626Pseudomonas aeruginosa, PSE-4 carbenicillinase [TaxId:287] [56610] (2 PDB entries)
    1. Domain for 1g68:
    2. Domain for 1g6a:
  13. 1690629Serratia marcescens, Sme-1 [TaxId:615] [56617] (1 PDB entry)
    imipenem-hydrolyzing
  14. 1690632Staphylococcus aureus [TaxId:1280] [56611] (16 PDB entries)
    1. Domain for 1alq:
    2. Domain for 1blc:
    3. Domain for 1blh:
    4. Domain for 1blp:
    5. Domain for 1dja:
    6. Domain for 1djb:
    7. Domain for 1djc:
    8. Domain for 1ghi:
    9. Domain for 1ghm:
    10. Domain for 1ghp:
    11. Domain for 1kge:
    12. Domain for 1kgf:
    13. Domain for 1kgg:
    14. Domains for 1ome:
      1. 1690648Domain d1omea_: 1ome A: [42717]
        omega loop deletion mutant (residues 163-178 deleted)
        complexed with cl; mutant
      2. 1690649Domain d1omeb_: 1ome B: [42718]
        omega loop deletion mutant (residues 163-178 deleted)
        complexed with cl; mutant
    15. Domains for 1pio:
      1. 1690646Domain d1pioa_: 1pio A: [42719]
      2. 1690647Domain d1piob_: 1pio B: [42720]
    16. Domain for 3blm:
  15. 1690651Stenotrophomonas maltophilia, L2 [TaxId:40324] [103374] (2 PDB entries)
    1. Domains for 1n4o:
      1. 1690654Domain d1n4oa_: 1n4o A: [91621]
        complexed with so4
      2. 1690655Domain d1n4ob_: 1n4o B: [91622]
        complexed with so4
    2. Domains for 1o7e:
      1. 1690652Domain d1o7ea_: 1o7e A: [92622]
        complexed with gol, so4
      2. 1690653Domain d1o7eb_: 1o7e B: [92623]
        complexed with gol, so4
  16. 1690656Streptomyces albus G [TaxId:1962] [56614] (1 PDB entry)

More info for Protein beta-Lactamase, class A from e.3.1.1: beta-Lactamase/D-ala carboxypeptidase

Timeline for Protein beta-Lactamase, class A from e.3.1.1: beta-Lactamase/D-ala carboxypeptidase: