SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family d.169.1.1: C-type lectin domain

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2208774Fold d.169: C-type lectin-like [56435] (1 superfamily)
    unusual fold
  4. 2208775Superfamily d.169.1: C-type lectin-like [56436] (9 families) (S)
  5. 2208776Family d.169.1.1: C-type lectin domain [56437] (29 protein domains)
    Pfam PF00059

Protein Domains:

  1. 2208777Aggrecan core protein [111260] (1 species)
  2. 2208780CD69 [56442] (1 species)
  3. 2208786CD94 [56440] (1 species)
  4. 2208795DC-SIGN (dendritic cell-specific ICAM-3 grabbing nonintegrin) [69855] (1 species)
  5. DC-SIGNR (DC-SIGN related receptor) [69857] (1 species)
  6. 2208824E-selectin, C-lectin domain [56456] (1 species)
    folowed by EGF-like module
  7. 2208828EBV gp42 [75583] (1 species)
  8. 2208831Eosinophil major basic protein [64457] (1 species)
  9. 2208837Galactose-specific C-type lectin [90061] (1 species)
  10. 2208849H1 subunit of the asialoglycoprotein receptor [56454] (1 species)
  11. 2208852Hypothetical protein F28B4.3 [118166] (1 species)
  12. 2208855Lectin CEL-I [111262] (1 species)
  13. 2208863Lectin TC14 [56463] (1 species)
  14. 2208869Lithostathine, inhibitor of stone formation [56438] (1 species)
  15. 2208873Low affinity immunoglobulin epsilon Fc receptor [143957] (1 species)
  16. 2208926Macrophage mannose receptor, CRD4 [56444] (1 species)
  17. 2208932Mannose-binding protein A, C-lectin domain [56458] (2 species)
    1. 2208933Species Human (Homo sapiens) [TaxId:9606] [56459] (1 PDB entry)
    2. 2208935Species Norway rat (Rattus norvegicus) [TaxId:10116] [56460] (38 PDB entries)
  18. 2209037NK cell receptor [56452] (3 species)
    1. 2209038Species Mouse (Mus musculus), ly49-a [TaxId:10090] [56453] (1 PDB entry)
    2. Species Mouse (Mus musculus), ly49-c [TaxId:10090] [103351] (2 PDB entries)
    3. 2209044Species Mouse (Mus musculus), ly49-i [TaxId:10090] [75582] (1 PDB entry)
  19. 2209047NK cell-activating receptor nkg2d [64453] (2 species)
    1. 2209048Species Human (Homo sapiens) [TaxId:9606] [64455] (4 PDB entries)
    2. 2209054Species Mouse (Mus musculus) [TaxId:10090] [64454] (2 PDB entries)
  20. 2209058Ovocleidin-17 [90059] (1 species)
    major protein of the eggshell calcified layer
  21. 2209061Oxidised low density lipoprotein [143955] (1 species)
  22. 2209064P-selectin, C-lectin domain [116731] (1 species)
    followed by EGF-like module
  23. 2209076Pancreatitis-associated protein 1 [103341] (1 species)
  24. 2209079Snake coagglutinin alpha chain [88861] (10 species)
    heterodimeric coagulation factors IX/X-binding protein (IX/X-BP)
    1. 2209080Species Habu snake (Trimeresurus flavoviridis) [TaxId:88087] [88862] (6 PDB entries)
    2. 2209090Species Habu snake (Trimeresurus flavoviridis), flavocetin-A [TaxId:88087] [88863] (1 PDB entry)
    3. 2209092Species Hundred-pace snake (Deinagkistrodon acutus), different isoforms [TaxId:36307] [88865] (3 PDB entries)
    4. 2209096Species Jararaca (Bothrops jararaca), botrocetin [TaxId:8724] [88864] (4 PDB entries)
    5. 2209102Species Malayan pit viper (Calloselasma rhodostoma), rhodocetin [TaxId:8717] [143953] (1 PDB entry)
      Uniprot P81397 1-132
    6. 2209104Species Puff adder (Bitis arietans), bitiscetin [TaxId:8692] [88866] (2 PDB entries)
    7. 2209107Species Saw-scaled viper (Echis carinatus), echicetin [TaxId:40353] [103346] (1 PDB entry)
    8. 2209109Species Snake (Echis multisquamatus), Ems16 [TaxId:93050] [103343] (2 PDB entries)
      Uniprot Q7T2Q1 24-157
    9. 2209112Species South american rattlesnake (Crotalus durissus terrificus), convulxin [TaxId:8732] [103344] (2 PDB entries)
    10. 2209117Species Taiwan habu (Trimeresurus mucrosquamatus), mucrocetin [TaxId:103944] [103345] (1 PDB entry)
  25. 2209121Snake coagglutinin beta chain [88867] (10 species)
    heterodimeric coagulation factors IX/X-binding protein (IX/X-BP)
    1. 2209122Species Habu snake (Trimeresurus flavoviridis) [TaxId:88087] [88868] (6 PDB entries)
    2. 2209132Species Habu snake (Trimeresurus flavoviridis), flavocetin-A [TaxId:88087] [88869] (1 PDB entry)
    3. 2209134Species Jararaca (Bothrops jararaca), botrocetin [TaxId:8724] [88870] (4 PDB entries)
    4. 2209140Species Malayan pit viper (Calloselasma rhodostoma), rhodocetin [TaxId:8717] [143954] (1 PDB entry)
      Uniprot P81398 2-128
    5. 2209142Species Puff adder (Bitis arietans), bitiscetin [TaxId:8692] [88872] (2 PDB entries)
    6. 2209145Species Saw-scaled viper (Echis carinatus), echicetin [TaxId:40353] [103350] (1 PDB entry)
    7. 2209147Species Sharp-nosed viper (Deinagkistrodon acutus) [TaxId:36307] [88871] (3 PDB entries)
    8. 2209151Species Snake (Echis multisquamatus), Ems16 [TaxId:93050] [103347] (2 PDB entries)
      Uniprot Q7T2Q0 27-153
    9. 2209154Species South american rattlesnake (Crotalus durissus terrificus), convulxin [TaxId:8732] [103348] (2 PDB entries)
    10. 2209159Species Taiwan habu (Trimeresurus mucrosquamatus), mucrocetin [TaxId:103944] [103349] (1 PDB entry)
  26. 2209163Surfactant protein, lectin domain [56461] (3 species)
    1. 2209164Species Human (Homo sapiens), SP-D [TaxId:9606] [56462] (9 PDB entries)
    2. 2209192Species Norway rat (Rattus norvegicus), SP-A [TaxId:10116] [103352] (15 PDB entries)
    3. 2209199Species Pig (Sus scrofa) [TaxId:9823] [226409] (1 PDB entry)
  27. 2209201Tetranectin [56465] (1 species)
    trimeric plasminogen binding protein with an alpha-helical coiled coil
  28. 2209206Type II antifreeze protein [56450] (1 species)
  29. 2209209automated matches [190329] (9 species)
    not a true protein
    1. 2209210Species Agkistrodon rhodostoma [TaxId:8717] [188575] (1 PDB entry)
    2. 2209215Species Brachyopsis rostratus [TaxId:412977] [188571] (1 PDB entry)
    3. 2209217Species Cucumaria echinata [TaxId:40245] [271988] (1 PDB entry)
    4. 2209222Species Human (Homo sapiens) [TaxId:9606] [187151] (9 PDB entries)
    5. 2209250Species Human herpesvirus 4 (strain b95-8) [TaxId:10377] [255828] (1 PDB entry)
    6. 2209253Species Malayan pit viper (Calloselasma rhodostoma) [TaxId:8717] [188489] (2 PDB entries)
    7. 2209263Species Mouse (Mus musculus) [TaxId:10090] [187300] (3 PDB entries)
    8. 2209269Species Sharp-nosed viper (Deinagkistrodon acutus) [TaxId:36307] [195597] (1 PDB entry)
    9. 2283562Species Bothrops jararacussu [TaxId:8726] [326863] (1 PDB entry)

More info for Family d.169.1.1: C-type lectin domain

Timeline for Family d.169.1.1: C-type lectin domain: