SCOP 1.67: Protein: Malate dehydrogenase

Lineage for Protein: Malate dehydrogenase

Root: SCOP 1.67
Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
unusual fold, defines family
Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families)
Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
Protein Malate dehydrogenase [56329] (11 species)

Species:

Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
1. Domain for 1b8p:
  - Domain d1b8pa2: 1b8p A:159-329 [42114]
    Other proteins in same PDB: d1b8pa1
2. Domain for 1b8u:
  - Domain d1b8ua2: 1b8u A:159-329 [42116]
    Other proteins in same PDB: d1b8ua1
    complexed with nad, oaa
3. Domain for 1b8v:
  - Domain d1b8va2: 1b8v A:159-329 [42115]
    Other proteins in same PDB: d1b8va1
    complexed with nah
Archaeon Haloarcula marismortui [TaxId:2238] [56335] (5 PDB entries)
1. Domains for 1d3a:
  1. Domain d1d3aa2: 1d3a A:163-330 [42110]
    Other proteins in same PDB: d1d3aa1, d1d3ab1
  2. Domain d1d3ab2: 1d3a B:163-330 [42111]
    Other proteins in same PDB: d1d3aa1, d1d3ab1
    complexed with cl, na
2. Domains for 1gt2:
  1. Domain d1gt2a2: 1gt2 A:163-330 [76339]
    Other proteins in same PDB: d1gt2a1, d1gt2b1
  2. Domain d1gt2b2: 1gt2 B:163-330 [76341]
    Other proteins in same PDB: d1gt2a1, d1gt2b1
    complexed with cl, na, nad; mutant
3. Domains for 1hlp:
  1. Domain d1hlpa2: 1hlp A:163-328 [42112]
    Other proteins in same PDB: d1hlpa1, d1hlpb1
  2. Domain d1hlpb2: 1hlp B:163-328 [42113]
    Other proteins in same PDB: d1hlpa1, d1hlpb1
    complexed with nad
4. Domains for 1o6z:
  1. Domain d1o6za2: 1o6z A:163-330 [81108]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
  2. Domain d1o6zb2: 1o6z B:163-330 [81110]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
  3. Domain d1o6zc2: 1o6z C:163-330 [81112]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
  4. Domain d1o6zd2: 1o6z D:163-330 [81114]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
    complexed with cl, nad; mutant
5. Domains for 2hlp:
  1. Domain d2hlpa2: 2hlp A:163-330 [42108]
    Other proteins in same PDB: d2hlpa1, d2hlpb1
  2. Domain d2hlpb2: 2hlp B:163-330 [42109]
    Other proteins in same PDB: d2hlpa1, d2hlpb1
Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
- Domains for 1gv0:
  1. Domain d1gv0a2: 1gv0 A:143-305 [65595]
    Other proteins in same PDB: d1gv0a1, d1gv0b1
  2. Domain d1gv0b2: 1gv0 B:143-305 [65597]
    Other proteins in same PDB: d1gv0a1, d1gv0b1
    complexed with nad
Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
1. Domains for 1guz:
  1. Domain d1guza2: 1guz A:143-305 [65587]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
  2. Domain d1guzb2: 1guz B:143-305 [65589]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
  3. Domain d1guzc2: 1guz C:143-305 [65591]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
  4. Domain d1guzd2: 1guz D:143-305 [65593]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
    complexed with nad
2. Domains for 1gv1:
  1. Domain d1gv1a2: 1gv1 A:143-305 [65599]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  2. Domain d1gv1b2: 1gv1 B:143-299 [65601]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  3. Domain d1gv1c2: 1gv1 C:143-305 [65603]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  4. Domain d1gv1d2: 1gv1 D:143-302 [65605]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
Chloroflexus aurantiacus [69840] (2 PDB entries)
1. Domains for 1guy:
  1. Domain d1guya2: 1guy A:144-306 [65583]
    Other proteins in same PDB: d1guya1, d1guyc1
  2. Domain d1guyc2: 1guy C:144-306 [65585]
    Other proteins in same PDB: d1guya1, d1guyc1
    complexed with cd, nad
2. Domains for 1ur5:
  1. Domain d1ur5a2: 1ur5 A:144-308 [99808]
    Other proteins in same PDB: d1ur5a1, d1ur5c1
  2. Domain d1ur5c2: 1ur5 C:144-309 [99810]
    Other proteins in same PDB: d1ur5a1, d1ur5c1
    complexed with cd, cl, na, nad; mutant
Escherichia coli [TaxId:562] [56333] (4 PDB entries)
1. Domain for 1emd:
  - Domain d1emd_2: 1emd 146-312 [42103]
    Other proteins in same PDB: d1emd_1
    complexed with cit, nad
2. Domains for 1ib6:
  1. Domain d1ib6a2: 1ib6 A:146-312 [62147]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
  2. Domain d1ib6b2: 1ib6 B:146-312 [62149]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
  3. Domain d1ib6c2: 1ib6 C:146-312 [62151]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
  4. Domain d1ib6d2: 1ib6 D:146-312 [62153]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
    complexed with nad, so4; mutant
3. Domains for 1ie3:
  1. Domain d1ie3a2: 1ie3 A:146-312 [62305]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
  2. Domain d1ie3b2: 1ie3 B:146-312 [62307]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
  3. Domain d1ie3c2: 1ie3 C:146-312 [62309]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
  4. Domain d1ie3d2: 1ie3 D:146-312 [62311]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
    complexed with nad, pyr; mutant
4. Domain for 2cmd:
  - Domain d2cmd_2: 2cmd 146-312 [42102]
    Other proteins in same PDB: d2cmd_1
    complexed with cit
Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
- Domain for 1civ:
  - Domain d1civa2: 1civ A:194-385 [42101]
    Other proteins in same PDB: d1civa1
    complexed with nap
Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
1. Domains for 1mld:
  1. Domain d1mlda2: 1mld A:145-313 [42089]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
  2. Domain d1mldb2: 1mld B:145-313 [42090]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
  3. Domain d1mldc2: 1mld C:145-313 [42091]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
  4. Domain d1mldd2: 1mld D:145-313 [42092]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
    complexed with cit
2. Domains for 4mdh:
  1. Domain d4mdha2: 4mdh A:155-333 [42095]
    Other proteins in same PDB: d4mdha1, d4mdhb1
  2. Domain d4mdhb2: 4mdh B:155-333 [42096]
    Other proteins in same PDB: d4mdha1, d4mdhb1
    complexed with nad, sul
3. Domains for 5mdh:
  1. Domain d5mdha2: 5mdh A:155-333 [42093]
    Other proteins in same PDB: d5mdha1, d5mdhb1
  2. Domain d5mdhb2: 5mdh B:155-333 [42094]
    Other proteins in same PDB: d5mdha1, d5mdhb1
    complexed with mak, nad
Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
- Domains for 7mdh:
  1. Domain d7mdha2: 7mdh A:198-385 [42097]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
  2. Domain d7mdhb2: 7mdh B:198-386 [42098]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
  3. Domain d7mdhc2: 7mdh C:198-384 [42099]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
  4. Domain d7mdhd2: 7mdh D:198-381 [42100]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
    complexed with zn; mutant
Thermus flavus [TaxId:274] [56334] (2 PDB entries)
1. Domains for 1bdm:
  1. Domain d1bdma2: 1bdm A:155-332 [42104]
    Other proteins in same PDB: d1bdma1, d1bdmb1
  2. Domain d1bdmb2: 1bdm B:155-332 [42105]
    Other proteins in same PDB: d1bdma1, d1bdmb1
    complexed with nax; mutant
2. Domains for 1bmd:
  1. Domain d1bmda2: 1bmd A:155-332 [42106]
    Other proteins in same PDB: d1bmda1, d1bmdb1
  2. Domain d1bmdb2: 1bmd B:155-332 [42107]
    Other proteins in same PDB: d1bmda1, d1bmdb1
    complexed with nad
Thermus thermophilus [TaxId:274] [82806] (1 PDB entry)
identical sequence to that from the Thermus flavus enzyme
- Domains for 1iz9:
  1. Domain d1iz9a2: 1iz9 A:155-327 [76985]
    Other proteins in same PDB: d1iz9a1, d1iz9b1
  2. Domain d1iz9b2: 1iz9 B:155-327 [76987]
    Other proteins in same PDB: d1iz9a1, d1iz9b1

More info for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain:

Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain first appeared (with stable ids) in SCOP 1.55
Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain appears in SCOP 1.65
Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain appears in SCOP 1.69
Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain appears in the current release, SCOPe 2.08