Lineage for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

  1. Root: SCOPe 2.01
  2. 1013083Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1047016Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 1047017Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families) (S)
  5. 1047018Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

Proteins:

  1. 1047019L-2-hydroxyisocapronate dehydrogenase, L-HICDH [56337] (1 species)
  2. 1047025Lactate dehydrogenase [56339] (15 species)
    1. 1047026Species Archaeoglobus fulgidus [TaxId:2234] [111253] (2 PDB entries)
      Uniprot O08349
    2. 1047029Species Bacillus stearothermophilus [TaxId:1422] [56344] (3 PDB entries)
    3. 1047046Species Bifidobacterium longum, strain am101-2 [TaxId:216816] [56346] (2 PDB entries)
    4. 1047051Species Clostridium thermocellum [TaxId:1515] [118160] (1 PDB entry)
      Uniprot Q4CDK5
    5. 1047053Species Dogfish (Squalus acanthias) [TaxId:7797] [56342] (3 PDB entries)
    6. 1047057Species Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [64444] (2 PDB entries)
    7. 1047064Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (1 PDB entry)
    8. 1047073Species Lactobacillus casei [TaxId:1582] [56345] (1 PDB entry)
    9. 1047075Species Lactobacillus pentosus [TaxId:1589] [69843] (1 PDB entry)
    10. 1047080Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [56343] (9 PDB entries)
    11. 1047090Species Mouse (Mus musculus) [TaxId:10090] [56341] (1 PDB entry)
    12. 1047095Species Pig (Sus scrofa) [TaxId:9823] [56340] (3 PDB entries)
    13. 1047101Species Plasmodium berghei [TaxId:5821] [103325] (7 PDB entries)
    14. 1047110Species Thermotoga maritima [TaxId:2336] [56347] (1 PDB entry)
    15. 1047112Species Toxoplasma gondii [TaxId:5811] [103326] (4 PDB entries)
  3. 1047126Malate dehydrogenase [56329] (11 species)
    1. 1047127Species Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
    2. 1047131Species Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
    3. 1047134Species Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
    4. 1047143Species Chloroflexus aurantiacus [TaxId:1108] [69840] (7 PDB entries)
      Uniprot P80040
    5. 1047158Species Escherichia coli [TaxId:562] [56333] (5 PDB entries)
    6. 1047173Species Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
    7. 1047175Species Haloarcula marismortui [TaxId:2238] [56335] (8 PDB entries)
    8. 1047200Species Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
    9. 1047209Species Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
    10. 1047214Species Thermus flavus [TaxId:274] [56334] (2 PDB entries)
    11. 1047219Species Thermus thermophilus [TaxId:274] [82806] (5 PDB entries)
      identical sequence to that from the Thermus flavus enzyme
  4. 1047230MJ0490, lactate/malate dehydrogenase [64446] (1 species)

More info for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain: