Lineage for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

  1. Root: SCOP 1.67
  2. 405194Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
  3. 420654Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 420655Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families) (S)
  5. 420656Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

Proteins:

  1. 420657L-2-hydroxyisocapronate dehydrogenase, L-HICDH [56337] (1 species)
  2. 420663Lactate dehydrogenase [56339] (13 species)
    1. 420664Species Bacillus stearothermophilus [TaxId:1422] [56344] (3 PDB entries)
    2. 420675Species Bifidobacterium longum, strain am101-2 [TaxId:216816] [56346] (2 PDB entries)
    3. 420680Species Dogfish (Squalus acanthias) [TaxId:7797] [56342] (3 PDB entries)
    4. 420684Species Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [64444] (2 PDB entries)
    5. 420691Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (1 PDB entry)
    6. 420700Species Lactobacillus casei [TaxId:1582] [56345] (1 PDB entry)
    7. 420702Species Lactobacillus pentosus [TaxId:1589] [69843] (1 PDB entry)
    8. 420707Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [56343] (9 PDB entries)
    9. 420717Species Mouse (Mus musculus) [TaxId:10090] [56341] (1 PDB entry)
    10. 420719Species Pig (Sus scrofa) [TaxId:9823] [56340] (3 PDB entries)
    11. 420725Species Plasmodium berghei [103325] (1 PDB entry)
    12. 420728Species Thermotoga maritima [TaxId:243274] [56347] (1 PDB entry)
    13. 420730Species Toxoplasma gondii [TaxId:5811] [103326] (4 PDB entries)
  3. 420744Malate dehydrogenase [56329] (11 species)
    1. 420745Species Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
    2. 420749Species Archaeon Haloarcula marismortui [TaxId:2238] [56335] (5 PDB entries)
    3. 420762Species Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
    4. 420765Species Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
    5. 420774Species Chloroflexus aurantiacus [69840] (2 PDB entries)
    6. 420779Species Escherichia coli [TaxId:562] [56333] (4 PDB entries)
    7. 420790Species Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
    8. 420792Species Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
    9. 420801Species Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
    10. 420806Species Thermus flavus [TaxId:274] [56334] (2 PDB entries)
    11. 420811Species Thermus thermophilus [TaxId:274] [82806] (1 PDB entry)
      identical sequence to that from the Thermus flavus enzyme
  4. 420814MJ0490, lactate/malate dehydrogenase [64446] (1 species)

More info for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain: