Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1934404Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 1934405Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 1934574Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

Proteins:

  1. 1934575HslV (ClpQ) protease [56258] (4 species)
    dodecameric prokaryotic homologue of proteasome
    1. 1934576Species Bacillus subtilis [TaxId:1423] [160845] (2 PDB entries)
      Uniprot P39070 2-181
    2. 1934591Species Escherichia coli [TaxId:562] [56259] (8 PDB entries)
    3. 1934639Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    4. 1934682Species Thermotoga maritima [TaxId:2336] [90045] (1 PDB entry)
  2. 1934686Proteasome alpha subunit (non-catalytic) [56255] (7 species)
    contains an extension to the common fold at the N-terminus
    1. 1934687Species Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 1934702Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (76 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 1935276Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256264] (1 PDB entry)
    4. 1935278Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    5. 1935293Species Mouse (Mus musculus) [TaxId:10090] [195927] (2 PDB entries)
    6. 1935298Species Rhodococcus erythropolis [TaxId:1833] [103314] (3 PDB entries)
    7. 1935320Species Thermoplasma acidophilum [TaxId:2303] [56256] (3 PDB entries)
  3. 1935363Proteasome beta subunit (catalytic) [56252] (5 species)
    1. 1935364Species Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 1935372Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (70 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 1936301Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    4. 1936316Species Rhodococcus erythropolis [TaxId:1833] [103313] (3 PDB entries)
    5. 1936338Species Thermoplasma acidophilum [TaxId:2303] [56253] (5 PDB entries)
  4. 1936395automated matches [190144] (7 species)
    not a true protein
    1. 1936396Species Bacillus anthracis [TaxId:198094] [189742] (1 PDB entry)
    2. 1936403Species Bacillus subtilis [TaxId:1423] [187296] (1 PDB entry)
    3. 1936416Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187078] (39 PDB entries)
    4. 1936658Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189752] (41 PDB entries)
    5. 1936958Species Mouse (Mus musculus) [TaxId:10090] [195917] (2 PDB entries)
    6. 1937002Species Mycobacterium tuberculosis [TaxId:1773] [187707] (9 PDB entries)
    7. 1937257Species Thermoplasma acidophilum [TaxId:2303] [186869] (7 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: