Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOP 1.71
  2. 595667Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
  3. 612721Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 612722Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 612861Family d.153.1.4: Proteasome subunits [56251] (3 proteins)

Proteins:

  1. 612862HslV (ClpQ) protease [56258] (3 species)
    dodecameric prokaryotic homologue of proteasome
    1. 612863Species Escherichia coli [TaxId:562] [56259] (7 PDB entries)
    2. 612899Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    3. 612942Species Thermotoga maritima [TaxId:243274] [90045] (1 PDB entry)
  2. 612946Proteasome alpha subunit (non-catalytic) [56255] (5 species)
    contains an extension to the common fold at the N-terminus
    1. 612947Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 612962Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56256] (1 PDB entry)
    3. 612977Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    4. 613034Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    5. 613049Species Rhodococcus erythropolis [103314] (2 PDB entries)
  3. 613064Proteasome beta subunit (catalytic) [56252] (5 species)
    1. 613065Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 613073Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56253] (1 PDB entry)
    3. 613088Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    4. 613145Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    5. 613160Species Rhodococcus erythropolis [103313] (2 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: