SCOPe 2.03: Superfamily d.148.1: Hect, E3 ligase catalytic domain

Lineage for Superfamily d.148.1: Hect, E3 ligase catalytic domain

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

Families:

1. d.148.1.1: Hect, E3 ligase catalytic domain [56205] (3 proteins)

2. d.148.1.0: automated matches [227207] (1 protein)
   not a true family

More info for Superfamily d.148.1: Hect, E3 ligase catalytic domain

Timeline for Superfamily d.148.1: Hect, E3 ligase catalytic domain:

• Superfamily d.148.1: Hect, E3 ligase catalytic domain first appeared (with stable ids) in SCOP 1.55, called Superfamily d.148.1: Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap)
  
• Superfamily d.148.1: Hect, E3 ligase catalytic domain appears in SCOPe 2.02
  
• Superfamily d.148.1: Hect, E3 ligase catalytic domain appears in SCOPe 2.04
  
• Superfamily d.148.1: Hect, E3 ligase catalytic domain appears in the current release, SCOPe 2.08