SCOP 1.63: Family d.144.1.2: Tyrosine kinase

Lineage for Family d.144.1.2: Tyrosine kinase

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.2: Tyrosine kinase [56150] (15 proteins)

Proteins:

1. Abelsone tyrosine kinase (abl) [56166] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [56167] (3 PDB entries)

2. Bruton's tyrosine kinase (Btk) [75564] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [75565] (1 PDB entry)

3. c-src tyrosine kinase [56155] (2 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [56156] (3 PDB entries)

4. Carboxyl-terminal src kinase (csk) [56164] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56165] (2 PDB entries)

5. EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82796] (2 PDB entries)

6. ephb2 receptor tyrosine kinase [69827] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [69828] (1 PDB entry)

7. Fibroblast growth factor receptor 1 [56158] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56159] (4 PDB entries)

8. Fibroblast growth factor receptor 2 [75562] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [75563] (1 PDB entry)

9. Haemopoetic cell kinase Hck [56151] (1 species)
   member of Src family

   • Species Human (Homo sapiens) [TaxId:9606] [56152] (3 PDB entries)

10. Insulin receptor [56162] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56163] (4 PDB entries)

11. Insulin-like growth factor 1 receptor [69825] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [69826] (3 PDB entries)

12. Lymphocyte kinase (lck) [56153] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56154] (5 PDB entries)

13. Musk tyrosine kinase [82797] (1 species)

    • Species Rat (Rattus norvegicus) [TaxId:10116] [82798] (1 PDB entry)

14. Tie2 kinase [64406] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [64407] (1 PDB entry)

15. Vascular endothelial growth factor receptor 2 (kdr) [56160] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56161] (1 PDB entry)

More info for Family d.144.1.2: Tyrosine kinase

Timeline for Family d.144.1.2: Tyrosine kinase:

• Family d.144.1.2: Tyrosine kinase first appeared (with stable ids) in SCOP 1.55
  
• Family d.144.1.2: Tyrosine kinase appears in SCOP 1.61
  
• Family d.144.1.2: Tyrosine kinase does not appear in SCOP 1.65