Lineage for Protein: MAP kinase Erk2

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2197339Protein MAP kinase Erk2 [56134] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase

Species:

  1. 2197340Human (Homo sapiens) [TaxId:9606] [56135] (31 PDB entries)
    1. Domain for 1pme:
    2. Domains for 4iz5:
      1. 2197368Domain d4iz5a_: 4iz5 A: [252764]
        automated match to d3sa0a_
        complexed with adp, so4; mutant
      2. 2197369Domain d4iz5b_: 4iz5 B: [252765]
        automated match to d3sa0a_
        complexed with adp, so4; mutant
      3. 2197370Domain d4iz5c_: 4iz5 C: [252766]
        automated match to d3sa0a_
        complexed with adp, so4; mutant
      4. 2197371Domain d4iz5d_: 4iz5 D: [252767]
        automated match to d3sa0a_
        complexed with adp, so4; mutant
    3. Domains for 4iz7:
      1. 2197341Domain d4iz7a_: 4iz7 A: [234921]
        automated match to d4iz7c_
        complexed with na
      2. 2197342Domain d4iz7c_: 4iz7 C: [196907]
        automated match to d3sa0a_
        complexed with na
    4. Domains for 4iza:
      1. 2197343Domain d4izaa_: 4iza A: [234920]
        automated match to d4iz7c_
      2. 2197344Domain d4izac_: 4iza C: [234922]
        automated match to d4iz7c_
    5. Domain for 4n0s:
    6. Domains for 4nif:
      1. 2197353Domain d4nifb_: 4nif B: [260917]
        Other proteins in same PDB: d4nifa_, d4nifd_
        automated match to d1erka_
        complexed with anp, na, so4
      2. 2197354Domain d4nife_: 4nif E: [260916]
        Other proteins in same PDB: d4nifa_, d4nifd_
        automated match to d1erka_
        complexed with anp, na, so4
    7. Domain for 4o6e:
    8. Domains for 4qp1:
      1. 2197372Domain d4qp1a_: 4qp1 A: [277294]
        automated match to d3sa0a_
        complexed with emu, imd
      2. 2197373Domain d4qp1b_: 4qp1 B: [277295]
        automated match to d3sa0a_
        complexed with emu, imd
    9. Domains for 4qp2:
      1. 2197357Domain d4qp2a_: 4qp2 A: [277298]
        automated match to d3sa0a_
        complexed with 36r, imd
      2. 2197358Domain d4qp2b_: 4qp2 B: [277300]
        automated match to d3sa0a_
        complexed with 36r, imd
    10. Domains for 4qp3:
      1. 2197366Domain d4qp3a_: 4qp3 A: [277285]
        automated match to d3sa0a_
        complexed with 36q
      2. 2197367Domain d4qp3b_: 4qp3 B: [277286]
        automated match to d3sa0a_
        complexed with 36q
    11. Domains for 4qp4:
      1. 2197355Domain d4qp4a_: 4qp4 A: [277289]
        automated match to d3sa0a_
        complexed with 36o
      2. 2197356Domain d4qp4b_: 4qp4 B: [277288]
        automated match to d3sa0a_
        complexed with 36o
    12. Domains for 4qp6:
      1. 2197376Domain d4qp6a_: 4qp6 A: [277297]
        automated match to d3sa0a_
        complexed with 36n, imd
      2. 2197377Domain d4qp6b_: 4qp6 B: [277293]
        automated match to d3sa0a_
        complexed with 36n, imd
    13. Domains for 4qp7:
      1. 2197359Domain d4qp7a_: 4qp7 A: [277290]
        automated match to d3sa0a_
        complexed with 363
      2. 2197360Domain d4qp7b_: 4qp7 B: [277301]
        automated match to d3sa0a_
        complexed with 363
    14. Domains for 4qp8:
      1. 2197362Domain d4qp8a_: 4qp8 A: [277292]
        automated match to d3sa0a_
        complexed with 362
      2. 2197363Domain d4qp8b_: 4qp8 B: [277296]
        automated match to d3sa0a_
        complexed with 362
    15. Domain for 4qp9:
    16. Domains for 4qpa:
      1. 2197374Domain d4qpaa_: 4qpa A: [277291]
        automated match to d3sa0a_
        complexed with 35w
      2. 2197375Domain d4qpab_: 4qpa B: [277299]
        automated match to d3sa0a_
        complexed with 35w
    17. Domains for 4xj0:
      1. 2197364Domain d4xj0a_: 4xj0 A: [277037]
        automated match to d1erka_
        complexed with 41b
      2. 2197365Domain d4xj0b_: 4xj0 B: [277036]
        automated match to d1erka_
        complexed with 41b
    18. Domain for 5bue:
    19. Domain for 5buj:
    20. Domain for 5bvd:
    21. Domain for 5bve:
    22. Domain for 5bvf:
    23. Domain for 5lcj:
    24. Domain for 5ngu:
    25. Domain for 5nhf:
    26. Domain for 5nhh:
    27. Domain for 5nhj:
    28. Domain for 5nhl:
    29. Domain for 5nho:
    30. Domain for 5nhp:
    31. Domain for 5nhv:
  2. 2197378Norway rat (Rattus norvegicus) [TaxId:10116] [56136] (36 PDB entries)
    1. Domain for 1erk:
    2. Domain for 1gol:
    3. Domain for 2erk:
    4. Domains for 2fys:
      1. 2197398Domain d2fysa_: 2fys A: [134389]
        automated match to d1erk__
      2. 2197399Domain d2fysb_: 2fys B: [134390]
        automated match to d1erk__
    5. Domain for 2gph:
    6. Domain for 2z7l:
    7. Domains for 3c9w:
      1. 2197401Domain d3c9wa2: 3c9w A:7-354 [156148]
        Other proteins in same PDB: d3c9wa3, d3c9wb3
        automated match to d2erka_
        complexed with hmy
      2. 2197402Domain d3c9wb2: 3c9w B:7-354 [156149]
        Other proteins in same PDB: d3c9wa3, d3c9wb3
        automated match to d2erka_
        complexed with hmy
    8. Domain for 3erk:
    9. Domain for 3o71:
    10. Domain for 3qyi:
    11. Domain for 3qyw:
    12. Domain for 3qyz:
    13. Domain for 3r63:
    14. Domain for 4erk:
    15. Domain for 4gsb:
    16. Domain for 4gt3:
    17. Domain for 4gva:
    18. Domain for 4i5h:
    19. Domains for 4n4s:
      1. 2197404Domain d4n4sa_: 4n4s A: [257124]
        automated match to d1erka_
        complexed with 2h1; mutant
      2. 2197405Domain d4n4sb_: 4n4s B: [257125]
        automated match to d1erka_
        complexed with 2h1; mutant
    20. Domain for 4qyy:
    21. Domain for 4s2z:
    22. Domain for 4s30:
    23. Domain for 4s31:
    24. Domain for 4s32:
    25. Domain for 4s33:
    26. Domain for 4s34:
    27. Domain for 4xne:
    28. Domain for 4xoy:
    29. Domain for 4xoz:
    30. Domain for 4xp0:
    31. Domain for 4xp2:
    32. Domain for 4xp3:
    33. Domain for 4xrj:
    34. Domain for 4xrl:
    35. Domain for 5hd4:
    36. Domain for 5hd7:

More info for Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit: