SCOPe 2.04: Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase

Lineage for Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.2: DNA ligase/mRNA capping enzyme, catalytic domain [56091] (6 families)
   has a circularly permuted topology

5. Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase [56096] (2 proteins)
   automatically mapped to Pfam PF01653

Proteins:

1. Adenylation domain of NAD+-dependent DNA ligase [56097] (4 species)
   contains additional, N-terminal all-alpha subdomain

   1. Species Bacillus stearothermophilus [TaxId:1422] [56098] (1 PDB entry)

   2. Species Enterococcus faecalis [TaxId:1351] [118124] (9 PDB entries)
      Uniprot Q837V6 5-317

   3. Species Staphylococcus aureus [TaxId:1280] [189155] (2 PDB entries)

   4. Species Thermus filiformis [TaxId:276] [56099] (2 PDB entries)

2. automated matches [194553] (2 species)
   not a true protein

   1. Species Enterococcus faecalis [TaxId:1351] [196940] (1 PDB entry)

   2. Species Streptococcus pneumoniae [TaxId:488223] [194554] (1 PDB entry)

More info for Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase

Timeline for Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase:

• Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase first appeared (with stable ids) in SCOP 1.55
  
• Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase appears in SCOPe 2.03
  
• Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase appears in SCOPe 2.05
  
• Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase appears in the current release, SCOPe 2.08