SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family d.131.1.2: DNA polymerase processivity factor

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2193533Fold d.131: DNA clamp [55978] (1 superfamily)
    contains two helices and two beta sheets
    duplication: fold has internal pseudo two-fold symmetry
  4. 2193534Superfamily d.131.1: DNA clamp [55979] (3 families) (S)
  5. 2193719Family d.131.1.2: DNA polymerase processivity factor [55983] (5 protein domains)
    duplication: consists of two domains of this fold

Protein Domains:

  1. 2193720gp45 sliding clamp [55984] (2 species)
    1. 2193721Species Bacteriophage RB69 [TaxId:12353] [55985] (2 PDB entries)
    2. 2193734Species Bacteriophage T4 [TaxId:10665] [55986] (1 PDB entry)
  2. 2193741Proliferating cell nuclear antigen (PCNA) [55989] (8 species)
    1. 2193742Species Archaeoglobus fulgidus [TaxId:2234] [103254] (3 PDB entries)
    2. 2193749Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55990] (6 PDB entries)
      Uniprot P15873
    3. 2193770Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [270905] (2 PDB entries)
    4. 2193773Species Haloferax volcanii [TaxId:2246] [225733] (1 PDB entry)
    5. 2193780Species Human (Homo sapiens) [TaxId:9606] [55991] (9 PDB entries)
      Uniprot P12004
    6. 2193831Species Pyrococcus furiosus [TaxId:2261] [55992] (4 PDB entries)
    7. 2193842Species Sulfolobus tokodaii [TaxId:111955] [111175] (1 PDB entry)
      Uniprot Q975N2
    8. 2272918Species Pyrococcus furiosus [TaxId:186497] [316219] (1 PDB entry)
  3. 2193851UL42 [55987] (1 species)
  4. 2193861UL44 [111176] (2 species)
    1. 2193862Species Human cytomegalovirus, HHV-5 [TaxId:10359] [111177] (2 PDB entries)
      Uniprot P16790 1-290
    2. 2283337Species Human cytomegalovirus (strain ad169) [TaxId:10360] [326638] (2 PDB entries)
  5. 2193867automated matches [227006] (4 species)
    not a true protein
    1. 2193868Species Archaeoglobus fulgidus [TaxId:2234] [256015] (1 PDB entry)
    2. 2193875Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [232312] (4 PDB entries)
    3. 2193882Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [233826] (5 PDB entries)
    4. 2193899Species Pyrococcus furiosus [TaxId:2261] [225778] (1 PDB entry)

More info for Family d.131.1.2: DNA polymerase processivity factor

Timeline for Family d.131.1.2: DNA polymerase processivity factor: