SCOP 1.69: Family d.122.1.2: DNA gyrase/MutL, N-terminal domain

Lineage for Family d.122.1.2: DNA gyrase/MutL, N-terminal domain

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.2: DNA gyrase/MutL, N-terminal domain [55879] (6 proteins)

Proteins:

1. DNA gyrase B [55880] (2 species)

   1. Species Escherichia coli [TaxId:562] [55881] (3 PDB entries)

   2. Species Thermus thermophilus [TaxId:274] [75534] (1 PDB entry)

2. DNA mismatch repair protein MutL [55882] (1 species)

   • Species Escherichia coli [TaxId:562] [55883] (6 PDB entries)

3. DNA mismatch repair protein PMS2 [69800] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69801] (3 PDB entries)

4. DNA topoisomerase II [103226] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [103227] (2 PDB entries)

5. Topoisomerase IV subunit B [103228] (1 species)

   • Species Escherichia coli [TaxId:562] [103229] (2 PDB entries)

6. Topoisomerase VI-B subunit [82778] (1 species)
   contains an H2TH domain inserted after this domain and before the second family-specific domain

   • Species Archaeon Sulfolobus shibatae [TaxId:2286] [82779] (2 PDB entries)

More info for Family d.122.1.2: DNA gyrase/MutL, N-terminal domain

Timeline for Family d.122.1.2: DNA gyrase/MutL, N-terminal domain:

• Family d.122.1.2: DNA gyrase/MutL, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family d.122.1.2: DNA gyrase/MutL, N-terminal domain appears in SCOP 1.67
  
• Family d.122.1.2: DNA gyrase/MutL, N-terminal domain appears in SCOP 1.71
  
• Family d.122.1.2: DNA gyrase/MutL, N-terminal domain appears in the current release, SCOPe 2.08