Species:

1. Cryptosporidium hominis [TaxId:237895] [100887] (16 PDB entries)

   1. Domains for 1qzf:

      1. Domain d1qzfa2: 1qzf A:181-521 [96634] Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1 complexed with cb3, fol, ndp, ump

      2. Domain d1qzfb2: 1qzf B:181-521 [96636] Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1 complexed with cb3, fol, ndp, ump

      3. Domain d1qzfc2: 1qzf C:181-521 [96638] Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1 complexed with cb3, fol, ndp, ump

      4. Domain d1qzfd2: 1qzf D:181-521 [96640] Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1 complexed with cb3, fol, ndp, ump

      5. Domain d1qzfe2: 1qzf E:181-521 [96642] Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1 complexed with cb3, fol, ndp, ump

   2. Domains for 1sej:

      1. Domain d1seja2: 1sej A:181-521 [105456] Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1 Q5CGA3 Q27552 complexed with f89, ndp, ump

      2. Domain d1sejb2: 1sej B:181-521 [105458] Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1 Q5CGA3 Q27552 complexed with f89, ndp, ump

      3. Domain d1sejc2: 1sej C:181-521 [105460] Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1 Q5CGA3 Q27552 complexed with f89, ndp, ump

      4. Domain d1sejd2: 1sej D:181-521 [105462] Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1 Q5CGA3 Q27552 complexed with f89, ndp, ump

      5. Domain d1seje2: 1sej E:181-521 [105464] Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1 Q5CGA3 Q27552 complexed with f89, ndp, ump

   3. Domains for 4ky8:

      1. Domain d4ky8a2: 4ky8 A:193-521 [253461] Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1 automated match to d1qzfa2 complexed with 1uf, mtx, ndp, ufp

      2. Domain d4ky8b2: 4ky8 B:193-521 [253463] Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1 automated match to d1qzfa2 complexed with 1uf, mtx, ndp, ufp

      3. Domain d4ky8c2: 4ky8 C:193-521 [253465] Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1 automated match to d1qzfa2 complexed with 1uf, mtx, ndp, ufp

      4. Domain d4ky8d2: 4ky8 D:193-521 [253467] Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1 automated match to d1qzfa2 complexed with 1uf, mtx, ndp, ufp

      5. Domain d4ky8e2: 4ky8 E:193-521 [253469] Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1 automated match to d1qzfa2 complexed with 1uf, mtx, ndp, ufp

   4. Domains for 4q0e:

      1. Domain d4q0ea2: 4q0e A:193-521 [260371] Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1 automated match to d1seja2 complexed with 2xb, ndp, ufp

      2. Domain d4q0eb2: 4q0e B:193-521 [260369] Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1 automated match to d1seja2 complexed with 2xb, ndp, ufp

      3. Domain d4q0ec2: 4q0e C:193-521 [260373] Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1 automated match to d1seja2 complexed with 2xb, ndp, ufp

      4. Domain d4q0ed2: 4q0e D:193-521 [260377] Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1 automated match to d1seja2 complexed with 2xb, ndp, ufp

      5. Domain d4q0ee2: 4q0e E:193-521 [260375] Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1 automated match to d1seja2 complexed with 2xb, ndp, ufp

   5. Domains for 6pf7:

      1. Domain d6pf7a2: 6pf7 A:193-521 [375066] Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1 automated match to d1qzfa2 complexed with mtx, ndp, og7, so4, ufp

      2. Domain d6pf7b2: 6pf7 B:193-521 [375112] Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1 automated match to d1qzfa2 complexed with mtx, ndp, og7, so4, ufp

      3. Domain d6pf7c2: 6pf7 C:181-521 [375139] Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1 automated match to d1qzfa2 complexed with mtx, ndp, og7, so4, ufp

      4. Domain d6pf7d2: 6pf7 D:193-521 [375064] Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1 automated match to d1qzfa2 complexed with mtx, ndp, og7, so4, ufp

      5. Domain d6pf7e2: 6pf7 E:181-521 [375130] Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1 automated match to d1qzfa2 complexed with mtx, ndp, og7, so4, ufp

   6. Domains for 6pf8:

      1. Domain d6pf8a2: 6pf8 A:193-521 [375077] Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1 automated match to d1qzfa2 complexed with mtx, ndp, oe7, ufp

      2. Domain d6pf8b2: 6pf8 B:193-521 [375135] Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1 automated match to d1qzfa2 complexed with mtx, ndp, oe7, ufp

      3. Domain d6pf8c2: 6pf8 C:193-521 [375122] Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1 automated match to d1qzfa2 complexed with mtx, ndp, oe7, ufp

      4. Domain d6pf8d2: 6pf8 D:193-521 [375096] Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1 automated match to d1qzfa2 complexed with mtx, ndp, oe7, ufp

      5. Domain d6pf8e2: 6pf8 E:193-521 [375045] Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1 automated match to d1qzfa2 complexed with mtx, ndp, oe7, ufp

   7. Domains for 6pf9:

      1. Domain d6pf9a2: 6pf9 A:193-521 [375068] Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1 automated match to d1qzfa2 complexed with mtx, ndp, of7, so4, ufp

      2. Domain d6pf9b2: 6pf9 B:193-521 [375109] Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1 automated match to d1qzfa2 complexed with mtx, ndp, of7, so4, ufp

      3. Domain d6pf9c2: 6pf9 C:193-521 [375094] Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1 automated match to d1qzfa2 complexed with mtx, ndp, of7, so4, ufp

      4. Domain d6pf9d2: 6pf9 D:193-521 [375073] Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1 automated match to d1qzfa2 complexed with mtx, ndp, of7, so4, ufp

      5. Domain d6pf9e2: 6pf9 E:193-521 [375047] Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1 automated match to d1qzfa2 complexed with mtx, ndp, of7, so4, ufp

   8. Domains for 6pfa:

      1. Domain d6pfaa2: 6pfa A:193-521 [375154] Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1 automated match to d1qzfa2 complexed with mtx, ndp, of4, so4, ufp

      2. Domain d6pfab2: 6pfa B:193-521 [375033] Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1 automated match to d1qzfa2 complexed with mtx, ndp, of4, so4, ufp

      3. Domain d6pfac2: 6pfa C:193-521 [375062] Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1 automated match to d1qzfa2 complexed with mtx, ndp, of4, so4, ufp

      4. Domain d6pfad2: 6pfa D:193-521 [375141] Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1 automated match to d1qzfa2 complexed with mtx, ndp, of4, so4, ufp

      5. Domain d6pfae2: 6pfa E:193-521 [375054] Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1 automated match to d1qzfa2 complexed with mtx, ndp, of4, so4, ufp

   9. Domains for 6pfb:

      1. Domain d6pfba2: 6pfb A:193-521 [375049] Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1 automated match to d1qzfa2 complexed with mtx, ndp, og4, ufp

      2. Domain d6pfbb2: 6pfb B:193-521 [375158] Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1 automated match to d1qzfa2 complexed with mtx, ndp, og4, ufp

      3. Domain d6pfbc2: 6pfb C:193-521 [375058] Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1 automated match to d1qzfa2 complexed with mtx, ndp, og4, ufp

      4. Domain d6pfbd2: 6pfb D:193-521 [375075] Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1 automated match to d1qzfa2 complexed with mtx, ndp, og4, ufp

      5. Domain d6pfbe2: 6pfb E:193-521 [375039] Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1 automated match to d1qzfa2 complexed with mtx, ndp, og4, ufp

   10. Domains for 6pfc:

       1. Domain d6pfca2: 6pfc A:193-521 [375816] Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1 automated match to d1qzfa2 complexed with mtx, ndp, oed, ufp

       2. Domain d6pfcb2: 6pfc B:193-521 [375820] Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1 automated match to d1qzfa2 complexed with mtx, ndp, oed, ufp

       3. Domain d6pfcc2: 6pfc C:193-521 [375828] Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1 automated match to d1qzfa2 complexed with mtx, ndp, oed, ufp

       4. Domain d6pfcd2: 6pfc D:193-521 [375844] Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1 automated match to d1qzfa2 complexed with mtx, ndp, oed, ufp

       5. Domain d6pfce2: 6pfc E:193-521 [375822] Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1 automated match to d1qzfa2 complexed with mtx, ndp, oed, ufp

   11. Domains for 6pfe:

       1. Domain d6pfea2: 6pfe A:193-521 [375035] Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1 automated match to d1qzfa2 complexed with mtx, ndp, oea, ufp

       2. Domain d6pfeb2: 6pfe B:193-521 [375235] Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1 automated match to d1qzfa2 complexed with mtx, ndp, oea, ufp

       3. Domain d6pfec2: 6pfe C:181-521 [375041] Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1 automated match to d1qzfa2 complexed with mtx, ndp, oea, ufp

       4. Domain d6pfed2: 6pfe D:181-521 [375083] Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1 automated match to d1qzfa2 complexed with mtx, ndp, oea, ufp

       5. Domain d6pfee2: 6pfe E:193-521 [375179] Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1 automated match to d1qzfa2 complexed with mtx, ndp, oea, ufp

   12. Domains for 6pff:

       1. Domain d6pffa2: 6pff A:193-521 [375092] Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1 automated match to d1qzfa2 complexed with mtx, ndp, og1, so4, ufp

       2. Domain d6pffb2: 6pff B:193-521 [375128] Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1 automated match to d1qzfa2 complexed with mtx, ndp, og1, so4, ufp

       3. Domain d6pffc2: 6pff C:193-521 [375148] Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1 automated match to d1qzfa2 complexed with mtx, ndp, og1, so4, ufp

       4. Domain d6pffd2: 6pff D:193-521 [375150] Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1 automated match to d1qzfa2 complexed with mtx, ndp, og1, so4, ufp

       5. Domain d6pffe2: 6pff E:193-521 [375185] Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1 automated match to d1qzfa2 complexed with mtx, ndp, og1, so4, ufp

   13. Domains for 6pfg:

       1. Domain d6pfga2: 6pfg A:193-521 [375029] Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1 automated match to d1qzfa2 complexed with mtx, ndp, ofj, so4, ufp

       2. Domain d6pfgb2: 6pfg B:193-521 [375070] Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1 automated match to d1qzfa2 complexed with mtx, ndp, ofj, so4, ufp

       3. Domain d6pfgc2: 6pfg C:193-521 [375031] Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1 automated match to d1qzfa2 complexed with mtx, ndp, ofj, so4, ufp

       4. Domain d6pfgd2: 6pfg D:193-521 [375100] Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1 automated match to d1qzfa2 complexed with mtx, ndp, ofj, so4, ufp

       5. Domain d6pfge2: 6pfg E:193-521 [375102] Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1 automated match to d1qzfa2 complexed with mtx, ndp, ofj, so4, ufp

   14. Domains for 6pfh:

       1. Domain d6pfha2: 6pfh A:181-521 [375051] Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1 automated match to d1qzfa2 complexed with mtx, ndp, ofd, ufp

       2. Domain d6pfhb2: 6pfh B:193-521 [375146] Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1 automated match to d1qzfa2 complexed with mtx, ndp, ofd, ufp

       3. Domain d6pfhc2: 6pfh C:193-521 [375087] Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1 automated match to d1qzfa2 complexed with mtx, ndp, ofd, ufp

       4. Domain d6pfhd2: 6pfh D:181-521 [375037] Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1 automated match to d1qzfa2 complexed with mtx, ndp, ofd, ufp

       5. Domain d6pfhe2: 6pfh E:193-521 [375166] Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1 automated match to d1qzfa2 complexed with mtx, ndp, ofd, ufp

   15. Domains for 6pfi:

       1. Domain d6pfia2: 6pfi A:193-521 [375107] Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1 automated match to d1qzfa2 complexed with mtx, ndp, oep, ufp

       2. Domain d6pfib2: 6pfi B:193-521 [375085] Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1 automated match to d1qzfa2 complexed with mtx, ndp, oep, ufp

       3. Domain d6pfic2: 6pfi C:193-521 [375060] Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1 automated match to d1qzfa2 complexed with mtx, ndp, oep, ufp

       4. Domain d6pfid2: 6pfi D:193-521 [375191] Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1 automated match to d1qzfa2 complexed with mtx, ndp, oep, ufp

       5. Domain d6pfie2: 6pfi E:193-521 [375056] Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1 automated match to d1qzfa2 complexed with mtx, ndp, oep, ufp

   16. Domains for 6wep:

       1. Domain d6wepa2: 6wep A:193-519 [388020] Other proteins in same PDB: d6wepa1, d6wepb1 automated match to d1qzfa2 complexed with mtx, ndp

       2. Domain d6wepb2: 6wep B:193-519 [388016] Other proteins in same PDB: d6wepa1, d6wepb1 automated match to d1qzfa2 complexed with mtx, ndp

2. Malaria parasite (Plasmodium falciparum) [TaxId:5833] [88964] (3 PDB entries)

   1. Domains for 1j3i:

      1. Domain d1j3ic_: 1j3i C: [84064] Other proteins in same PDB: d1j3ia_, d1j3ib_ complexed with ndp, ump, wra

      2. Domain d1j3id_: 1j3i D: [84065] Other proteins in same PDB: d1j3ia_, d1j3ib_ complexed with ndp, ump, wra

   2. Domains for 1j3j:

      1. Domain d1j3jc_: 1j3j C: [84068] Other proteins in same PDB: d1j3ja_, d1j3jb_ complexed with cp6, ndp, ump; mutant

      2. Domain d1j3jd_: 1j3j D: [84069] Other proteins in same PDB: d1j3ja_, d1j3jb_ complexed with cp6, ndp, ump; mutant

   3. Domains for 1j3k:

      1. Domain d1j3kc_: 1j3k C: [84072] Other proteins in same PDB: d1j3ka_, d1j3kb_ complexed with ndp, ump, wra; mutant

      2. Domain d1j3kd_: 1j3k D: [84073] Other proteins in same PDB: d1j3ka_, d1j3kb_ complexed with ndp, ump, wra; mutant

More info for Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase

Timeline for Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase:

• Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase first appeared (with stable ids) in SCOP 1.55, called Protein Bifunctional enzyme dihidrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase
  
• Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase appears in SCOPe 2.07