Lineage for Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2190102Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2190103Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2190104Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 protein domains)

Protein Domains:

  1. 2190105Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)
    1. 2190106Species Cryptosporidium hominis [TaxId:237895] [100887] (4 PDB entries)
    2. 2190127Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [88964] (3 PDB entries)
  2. 2190134dCMP hydroxymethylase [55843] (1 species)
  3. 2190142Thymidylate synthase [55833] (7 species)
    1. 2190143Species Bacillus subtilis [TaxId:1423] [55836] (5 PDB entries)
    2. 2190155Species Bacteriophage T4 [TaxId:10665] [55837] (1 PDB entry)
    3. 2190157Species Escherichia coli [TaxId:562] [55834] (67 PDB entries)
    4. 2190276Species Fungus (Pneumocystis carinii) [TaxId:4754] [55838] (2 PDB entries)
    5. 2190283Species Human (Homo sapiens) [TaxId:9606] [55840] (26 PDB entries)
    6. 2190340Species Lactobacillus casei [TaxId:1582] [55835] (51 PDB entries)
    7. 2190392Species Norway rat (Rattus norvegicus) [TaxId:10116] [55839] (2 PDB entries)
  4. 2190399automated matches [190469] (14 species)
    not a true protein
    1. 2190400Species Corynebacterium glutamicum [TaxId:196627] [227854] (2 PDB entries)
    2. 2190407Species Cryptosporidium hominis [TaxId:237895] [232024] (3 PDB entries)
    3. 2190420Species Encephalitozoon cuniculi [TaxId:284813] [189107] (1 PDB entry)
    4. 2190422Species Enterococcus faecalis [TaxId:1351] [194752] (3 PDB entries)
    5. 2190431Species Fungus (Filobasidiella neoformans) [TaxId:5207] [187389] (1 PDB entry)
    6. 2190448Species Human (Homo sapiens) [TaxId:9606] [189245] (17 PDB entries)
    7. 2190467Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [188759] (2 PDB entries)
    8. 2190472Species Mouse (Mus musculus) [TaxId:10090] [225826] (7 PDB entries)
    9. 2190494Species Mycobacterium tuberculosis [TaxId:1773] [189990] (2 PDB entries)
    10. 2190503Species Mycobacterium tuberculosis [TaxId:83332] [224938] (3 PDB entries)
    11. 2190518Species Staphylococcus aureus [TaxId:158878] [195805] (1 PDB entry)
    12. 2190521Species Trichinella spiralis [TaxId:6334] [226731] (1 PDB entry)
    13. 2190526Species Varicella-zoster virus (strain oka vaccine) [TaxId:341980] [311478] (3 PDB entries)
    14. 2285170Species Human herpesvirus 8 [TaxId:37296] [328471] (3 PDB entries)

More info for Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase

Timeline for Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase: