SCOP 1.71: Superfamily d.113.1: Nudix

Lineage for Superfamily d.113.1: Nudix

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.113: Nudix [55810] (1 superfamily)
   beta(2)-alpha-beta(3)-alpha; 3 layers: alpha/beta/alpha; mixed sheet
   contains beta-grasp motif

4. Superfamily d.113.1: Nudix [55811] (5 families)

Families:

1. d.113.1.1: MutT-like [55812] (10 proteins)

2. d.113.1.2: IPP isomerase-like [64369] (2 proteins)

3. d.113.1.3: Adenine glycosylase MutY, C-terminal domain [103211] (1 protein)

4. d.113.1.4: NADH pyrophosphatase [103214] (1 protein)
   duplication: consists of two structurally similar domains separated by a rubredoxin-like zinc finger; the N-terminal domain has a rudiment Nudix fold, the C-terminal, probably catalytic, domain has the canonical fold

5. d.113.1.5: GDP-mannose mannosyl hydrolase NudD [111132] (1 protein)

More info for Superfamily d.113.1: Nudix

Timeline for Superfamily d.113.1: Nudix:

• Superfamily d.113.1: Nudix first appeared (with stable ids) in SCOP 1.55, called Superfamily d.113.1: Nucleoside triphosphate pyrophosphorylase (MutT)
  
• Superfamily d.113.1: Nudix appears in SCOP 1.69
  
• Superfamily d.113.1: Nudix appears in SCOP 1.73
  
• Superfamily d.113.1: Nudix appears in the current release, SCOPe 2.08