SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family d.58.6.1: Nucleoside diphosphate kinase, NDK

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2172288Fold d.58: Ferredoxin-like [54861] (59 superfamilies)
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. 2173863Superfamily d.58.6: Nucleoside diphosphate kinase, NDK [54919] (2 families) (S)
  5. 2173864Family d.58.6.1: Nucleoside diphosphate kinase, NDK [54920] (2 protein domains)

Protein Domains:

  1. 2173865Nucleoside diphosphate kinase, NDK [54921] (23 species)
    1. 2173866Species Acanthamoeba polyphaga mimivirus [TaxId:212035] [224931] (1 PDB entry)
    2. 2173873Species Bacillus halodenitrificans [TaxId:1482] [89937] (1 PDB entry)
    3. 2173875Species Cow (Bos taurus) [TaxId:9913] [54924] (2 PDB entries)
    4. 2173885Species Escherichia coli [TaxId:562] [187827] (1 PDB entry)
    5. 2173892Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [54926] (2 PDB entries)
    6. 2173899Species Haloarcula quadrata [TaxId:182779] [225752] (1 PDB entry)
    7. 2173904Species Halobacterium salinarum [TaxId:2242] [143288] (2 PDB entries)
      Uniprot P61136 4-158
    8. 2173920Species Human (Homo sapiens) [TaxId:9606] [54922] (5 PDB entries)
    9. 2173951Species Human (Homo sapiens), NDK3 [TaxId:9606] [143283] (1 PDB entry)
      Uniprot Q13232 18-169
    10. 2173955Species Human (Homo sapiens), NDK4 [TaxId:9606] [54923] (1 PDB entry)
    11. 2173958Species Human (Homo sapiens), NDKA [TaxId:9606] [75437] (6 PDB entries)
    12. 2173979Species Mimivirus [TaxId:315393] [143286] (2 PDB entries)
      Uniprot Q5UQL3 2-137
    13. 2173988Species Mycobacterium tuberculosis [TaxId:1773] [75438] (1 PDB entry)
    14. 2173995Species Myxococcus xanthus [TaxId:34] [54927] (3 PDB entries)
    15. 2174002Species Pea (Pisum sativum) [TaxId:3888] [117948] (1 PDB entry)
      Uniprot Q9SP13 81-231
    16. 2174009Species Plasmodium falciparum, isolate 3D7 [TaxId:5833] [117947] (1 PDB entry)
      Uniprot Q8ID43
    17. 2174016Species Pyrobaculum aerophilum [TaxId:13773] [143287] (1 PDB entry)
      Uniprot Q8ZWY4 2-183
    18. 2174020Species Pyrococcus horikoshii [TaxId:53953] [143284] (6 PDB entries)
      Uniprot O58429 3-155
    19. 2174032Species Rice (Oryza sativa) [TaxId:4530] [143285] (1 PDB entry)
      Uniprot Q07661 1-148
    20. 2174034Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [54925] (22 PDB entries)
    21. 2174087Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117949] (1 PDB entry)
      Uniprot P39207
    22. 2174094Species Thale cress (Arabidopsis thaliana), chloroplast NDK2 [TaxId:3702] [117950] (2 PDB entries)
      Uniprot O64903 79-231
    23. 2174107Species Thermus thermophilus [TaxId:274] [143289] (3 PDB entries)
      Uniprot Q5SLV5 1-137
  2. 2174114automated matches [190032] (16 species)
    not a true protein
    1. 2174115Species Acanthamoeba polyphaga mimivirus [TaxId:212035] [188891] (23 PDB entries)
    2. 2174214Species Acinetobacter baumannii [TaxId:509170] [273931] (1 PDB entry)
    3. 2174216Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [188810] (1 PDB entry)
    4. 2174218Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [255759] (1 PDB entry)
    5. 2174221Species Burkholderia thailandensis [TaxId:271848] [193397] (3 PDB entries)
    6. 2174228Species Campylobacter jejuni [TaxId:192222] [189538] (1 PDB entry)
    7. 2174233Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [273749] (1 PDB entry)
    8. 2174237Species Giardia lamblia [TaxId:184922] [189932] (1 PDB entry)
    9. 2174239Species Leishmania braziliensis [TaxId:5660] [257801] (1 PDB entry)
    10. 2174242Species Leishmania major [TaxId:5664] [189935] (7 PDB entries)
    11. 2174270Species Pyrococcus horikoshii OT3 [TaxId:70601] [187576] (1 PDB entry)
    12. 2174272Species Rice (Oryza sativa) [TaxId:4530] [186751] (1 PDB entry)
    13. 2174284Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [186756] (3 PDB entries)
    14. 2174298Species Staphylococcus aureus [TaxId:93062] [196295] (6 PDB entries)
    15. 2174337Species Toxoplasma gondii [TaxId:508771] [230191] (2 PDB entries)
    16. 2287358Species Schistosoma mansoni [TaxId:6183] [330659] (1 PDB entry)

More info for Family d.58.6.1: Nucleoside diphosphate kinase, NDK

Timeline for Family d.58.6.1: Nucleoside diphosphate kinase, NDK: