SCOP 1.73: Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

Lineage for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.51: Eukaryotic type KH-domain (KH-domain type I) [54790] (1 superfamily)
   beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

4. Superfamily d.51.1: Eukaryotic type KH-domain (KH-domain type I) [54791] (1 family)
   Prokaryotic and eukaryotic domains share a KH-motif but have different topologies

5. Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) [54792] (13 proteins)
   an RNA-binding domain

Proteins:

1. Far upstream binding element, FBP [75418] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [75419] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [143219] (2 PDB entries)

2. Fragile X mental retardation syndrome related protein 1, FXR1 [143222] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [143223] (1 PDB entry)

3. Fragile X protein, KH1 [54799] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54800] (1 PDB entry)

4. HnRNP K, KH3 [54801] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54802] (5 PDB entries)

5. Hypothetical protein APE0754 [110927] (1 species)
   duplication: tandem repeat of two KH-1 domains

   • Species Aeropyrum pernix [TaxId:56636] [110928] (1 PDB entry)

6. Neuro-oncological ventral antigen 1, nova-1, KH3 [54793] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54794] (1 PDB entry)

7. Neuro-oncological ventral antigen 2, nova-2, KH3 [54795] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54796] (2 PDB entries)

8. Poly(RC)-binding protein 1 [143224] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [143225] (1 PDB entry)

9. Poly(RC)-binding protein 2 [143220] (1 species)
   contains three KH domains

   • Species Human (Homo sapiens) [TaxId:9606] [143221] (3 PDB entries)

10. Quaking protein A (Xqua) [143226] (1 species)

    • Species African clawed frog (Xenopus laevis) [TaxId:8355] [143227] (1 PDB entry)

11. RNA splicing factor 1 [69699] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [69700] (1 PDB entry)

12. Tudor and KH domain containing protein, Tdrkh [117912] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [117913] (1 PDB entry)

13. Vigilin [54797] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [54798] (8 PDB entries)

More info for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

Timeline for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I):

• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) first appeared (with stable ids) in SCOP 1.55, called Family d.51.1.1: KH-domain
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in SCOP 1.71
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in SCOP 1.75
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in the current release, SCOPe 2.08