SCOP 1.69: Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

Lineage for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.51: Eukaryotic type KH-domain (KH-domain type I) [54790] (1 superfamily)
   beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

4. Superfamily d.51.1: Eukaryotic type KH-domain (KH-domain type I) [54791] (1 family)
   Prokaryotic and eukaryotic domains share a KH-motif but have different topologies

5. Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) [54792] (8 proteins)
   an RNA-binding domain

Proteins:

1. Far upstream binding element, FBP, KH3 and KH4 domains [75418] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [75419] (1 PDB entry)

2. Fragile X protein, KH1 [54799] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54800] (1 PDB entry)

3. HnRNP K, KH3 [54801] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54802] (2 PDB entries)

4. Hypothetical protein APE0754 [110927] (1 species)
   duplication: tandem repeat of two KH-1 domains

   • Species Aeropyrum pernix [TaxId:56636] [110928] (1 PDB entry)

5. Neuro-oncological ventral antigen 1, nova-1, KH3 [54793] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54794] (1 PDB entry)

6. Neuro-oncological ventral antigen 2, nova-2, KH3 [54795] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54796] (2 PDB entries)

7. RNA splicing factor 1 [69699] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69700] (1 PDB entry)

8. Vigilin, KH6 [54797] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54798] (2 PDB entries)

More info for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I)

Timeline for Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I):

• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) first appeared (with stable ids) in SCOP 1.55, called Family d.51.1.1: KH-domain
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in SCOP 1.67
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in SCOP 1.71
  
• Family d.51.1.1: Eukaryotic type KH-domain (KH-domain type I) appears in the current release, SCOPe 2.08