Lineage for Family d.50.1.1: Double-stranded RNA-binding domain (dsRBD)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1202665Fold d.50: dsRBD-like [54767] (5 superfamilies)
    alpha-beta(3)-alpha; 2 layers: alpha/beta
  4. 1202666Superfamily d.50.1: dsRNA-binding domain-like [54768] (3 families) (S)
  5. 1202667Family d.50.1.1: Double-stranded RNA-binding domain (dsRBD) [54769] (13 proteins)
    Pfam PF00035

Proteins:

  1. 1202668ATP-dependent RNA helicase A, Dhx9 [117901] (1 species)
    formerly hypothetical protein bab28848
  2. 1202672Dgcr8 protein [143206] (1 species)
  3. 1202675Double-stranded RNA-binding protein A, second dsRBD [54770] (1 species)
  4. 1202679dsRNA-dependent protein kinase pkr [54774] (2 species)
    contains tandem repeat of two dsRBD
    1. 1202680Species Human (Homo sapiens) [TaxId:9606] [54775] (1 PDB entry)
    2. 1202683Species Mouse (Mus musculus) [TaxId:10090] [143201] (2 PDB entries)
      Uniprot Q03963 1-85! Uniprot Q03963 96-181
  5. 1202686dsRNA-specific editase 1 [143202] (1 species)
    duplication: contains two dsRBD domains
  6. 1202690Interferon-inducible double stranded RNA-dependent protein kinase activator A [143204] (1 species)
  7. 1202693RNase III, C-terminal domain [54776] (3 species)
    1. 1202694Species Aquifex aeolicus [TaxId:63363] [102927] (9 PDB entries)
    2. 1202714Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110913] (3 PDB entries)
      Uniprot Q02555 364-447 ! Uniprot Q02555 366-453 ! Uniprot Q02555 363-443
    3. 1202719Species Thermotoga maritima [TaxId:2336] [82644] (1 PDB entry)
  8. 1202722Spermatid perinuclear RNA-binding protein [143210] (1 species)
  9. 1202725staufen homolog 2 [110914] (1 species)
  10. 1202728Staufen, domain III [54772] (1 species)
  11. 1202732TAR RNA-binding protein 2 [143208] (1 species)
    duplication: contains three dsRBD
  12. 1202735tRNA-dihydrouridine synthase 2-like, Dus2l (2310016k04Rik) [117903] (1 species)
  13. 1202738automated matches [191157] (1 species)
    not a true protein

More info for Family d.50.1.1: Double-stranded RNA-binding domain (dsRBD)

Timeline for Family d.50.1.1: Double-stranded RNA-binding domain (dsRBD):