Lineage for Species: Human (Homo sapiens), type II [TaxId: 9606]

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 858507Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 858508Superfamily d.37.1: CBS-domain pair [54631] (1 family) (S)
  5. 858509Family d.37.1.1: CBS-domain pair [54632] (20 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. 858568Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 858574Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens), type II [TaxId: 9606]:

  1. Domain(s) for 1b3o:
  2. Domain(s) for 1nf7:
    1. 858576Domain d1nf7a4: 1nf7 A:112-231 [144359]
      Other proteins in same PDB: d1nf7a1, d1nf7b1
      both CBS motifs are partly disordered in both chains, A and B
    2. 858577Domain d1nf7b4: 1nf7 B:112-231 [144360]
      Other proteins in same PDB: d1nf7a1, d1nf7b1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with k, myd, rvp
  3. Domain(s) for 1nfb:
    1. 858578Domain d1nfba4: 1nfb A:112-231 [144361]
      Other proteins in same PDB: d1nfba1, d1nfbb1
      both CBS motifs are partly disordered in both chains, A and B
    2. 858579Domain d1nfbb4: 1nfb B:112-231 [144362]
      Other proteins in same PDB: d1nfba1, d1nfbb1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with cpr, nad

More info for Species Human (Homo sapiens), type II [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains

Timeline for Species Human (Homo sapiens), type II [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains: