Lineage for Protein: 4-hydroxyphenylpyruvate dioxygenase, HppD

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1900809Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 1900810Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 1900969Family d.32.1.3: Extradiol dioxygenases [54602] (5 proteins)
    duplication: consists of 2 similar domains with 2 repeats in each
    Similar to the Methylmalonyl-CoA epimerase dimer
  6. 1901005Protein 4-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)

Species:

  1. 1901006Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)
  2. 1901009Maize (Zea mays) [TaxId:4577] [110879] (1 PDB entry)
    Uniprot O48604 29-423 # 85% sequence identity
  3. 1901018Norway rat (Rattus norvegicus) [TaxId:10116] [256396] (1 PDB entry)
    Uniprot P32755
  4. 1901023Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)
  5. 1901032Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)
    Uniprot Q53586
  6. 1901037Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (4 PDB entries)
    Uniprot P93836 33-428 ! Uniprot P93836 63-459
    1. Domains for 1sp9:
      1. 1901044Domain d1sp9a1: 1sp9 A:33-232 [238534]
        complexed with fe2
      2. 1901045Domain d1sp9a2: 1sp9 A:233-428 [238535]
        complexed with fe2
      3. 1901046Domain d1sp9b1: 1sp9 B:33-193 [238536]
        automated match to d1tg5a1
        complexed with fe2
      4. 1901047Domain d1sp9b2: 1sp9 B:202-437 [238537]
        automated match to d1tg5a2
        complexed with fe2
    2. Domains for 1sqd:
      1. 1901042Domain d1sqda1: 1sqd A:14-195 [105906]
        complexed with fe
      2. 1901043Domain d1sqda2: 1sqd A:196-410 [105907]
        complexed with fe
    3. Domains for 1tfz:
      1. 1901038Domain d1tfza1: 1tfz A:15-195 [106886]
        complexed with 869, fe
      2. 1901039Domain d1tfza2: 1tfz A:196-408 [106887]
        complexed with 869, fe
    4. Domains for 1tg5:
      1. 1901040Domain d1tg5a1: 1tg5 A:14-195 [106890]
        complexed with 645, fe2
      2. 1901041Domain d1tg5a2: 1tg5 A:196-410 [106891]
        complexed with 645, fe2

More info for Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases

Timeline for Protein 4-hydroxyphenylpyruvate dioxygenase, HppD from d.32.1.3: Extradiol dioxygenases: