Lineage for Protein: 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1900809Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 1900810Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 1900969Family d.32.1.3: Extradiol dioxygenases [54602] (5 proteins)
    duplication: consists of 2 similar domains with 2 repeats in each
    Similar to the Methylmalonyl-CoA epimerase dimer
  6. 1900970Protein 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603] (2 species)

Species:

  1. 1900971Burkholderia cepacia, formerly Pseudomonas cepacia [TaxId:292] [54605] (6 PDB entries)
    1. Domains for 1han:
      1. 1900976Domain d1hana1: 1han A:2-132 [38506]
        CASP1
        complexed with fe, tbu
      2. 1900977Domain d1hana2: 1han A:133-289 [38507]
        CASP1
        complexed with fe, tbu
    2. Domains for 1kmy:
      1. 1900982Domain d1kmya1: 1kmy A:2-132 [68697]
        complexed with bpy, fe2, tbu
      2. 1900983Domain d1kmya2: 1kmy A:133-289 [68698]
        complexed with bpy, fe2, tbu
    3. Domains for 1knd:
      1. 1900978Domain d1knda1: 1knd A:2-132 [72772]
        complexed with caq, fe2, tbu
      2. 1900979Domain d1knda2: 1knd A:133-289 [72773]
        complexed with caq, fe2, tbu
    4. Domains for 1knf:
      1. 1900980Domain d1knfa1: 1knf A:2-132 [72775]
        complexed with fe2, mbd, tbu
      2. 1900981Domain d1knfa2: 1knf A:133-289 [72776]
        complexed with fe2, mbd, tbu
    5. Domains for 1lgt:
      1. 1900974Domain d1lgta1: 1lgt A:2-132 [77956]
        complexed with bp3, fe2
      2. 1900975Domain d1lgta2: 1lgt A:133-288 [77957]
        complexed with bp3, fe2
    6. Domains for 1lkd:
      1. 1900972Domain d1lkda1: 1lkd A:2-132 [78059]
        complexed with bp6, fe2, p6g
      2. 1900973Domain d1lkda2: 1lkd A:133-288 [78060]
        complexed with bp6, fe2, p6g
  2. 1900984Pseudomonas sp. [TaxId:306] [54604] (10 PDB entries)
    1. Domains for 1dhy:
      1. 1901003Domain d1dhya1: 1dhy A:1-132 [38504]
        complexed with fe
      2. 1901004Domain d1dhya2: 1dhy A:133-288 [38505]
        complexed with fe
    2. Domains for 1eil:
      1. 1901001Domain d1eila1: 1eil A:1-132 [38502]
        complexed with fe, so4
      2. 1901002Domain d1eila2: 1eil A:133-289 [38503]
        complexed with fe, so4
    3. Domains for 1eiq:
      1. 1900999Domain d1eiqa1: 1eiq A:1-132 [38498]
        complexed with fe
      2. 1901000Domain d1eiqa2: 1eiq A:133-289 [38499]
        complexed with fe
    4. Domains for 1eir:
      1. 1900997Domain d1eira1: 1eir A:1-132 [38500]
        complexed with bpy, fe
      2. 1900998Domain d1eira2: 1eir A:133-289 [38501]
        complexed with bpy, fe
    5. Domains for 1kw3:
      1. 1900985Domain d1kw3b1: 1kw3 B:1-132 [77549]
        complexed with fe2, mpd
      2. 1900986Domain d1kw3b2: 1kw3 B:133-288 [77550]
        complexed with fe2, mpd
    6. Domains for 1kw6:
      1. 1900987Domain d1kw6b1: 1kw6 B:1-132 [77551]
        complexed with bpy, fe2, mpd
      2. 1900988Domain d1kw6b2: 1kw6 B:133-288 [77552]
        complexed with bpy, fe2, mpd
    7. Domains for 1kw8:
      1. 1900991Domain d1kw8b1: 1kw8 B:1-132 [77553]
        complexed with bpy, fe2, no
      2. 1900992Domain d1kw8b2: 1kw8 B:133-288 [77554]
        complexed with bpy, fe2, no
    8. Domains for 1kw9:
      1. 1900989Domain d1kw9b1: 1kw9 B:1-132 [77555]
        complexed with bpy, fe2
      2. 1900990Domain d1kw9b2: 1kw9 B:133-288 [77556]
        complexed with bpy, fe2
    9. Domains for 1kwb:
      1. 1900993Domain d1kwbb1: 1kwb B:1-132 [77557]
        mutant
      2. 1900994Domain d1kwbb2: 1kwb B:133-288 [77558]
        mutant
    10. Domains for 1kwc:
      1. 1900995Domain d1kwcb1: 1kwc B:1-132 [77559]
        complexed with bpy; mutant
      2. 1900996Domain d1kwcb2: 1kwc B:133-288 [77560]
        complexed with bpy; mutant

More info for Protein 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) from d.32.1.3: Extradiol dioxygenases

Timeline for Protein 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) from d.32.1.3: Extradiol dioxygenases: