Lineage for Family d.32.1.3: Extradiol dioxygenases

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1900809Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 1900810Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 1900969Family d.32.1.3: Extradiol dioxygenases [54602] (5 proteins)
    duplication: consists of 2 similar domains with 2 repeats in each
    Similar to the Methylmalonyl-CoA epimerase dimer

Proteins:

  1. 19009702,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603] (2 species)
    1. 1900971Species Burkholderia cepacia, formerly Pseudomonas cepacia [TaxId:292] [54605] (6 PDB entries)
    2. 1900984Species Pseudomonas sp. [TaxId:306] [54604] (10 PDB entries)
  2. 19010054-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)
    1. 1901006Species Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)
    2. 1901009Species Maize (Zea mays) [TaxId:4577] [110879] (1 PDB entry)
      Uniprot O48604 29-423 # 85% sequence identity
    3. 1901018Species Norway rat (Rattus norvegicus) [TaxId:10116] [256396] (1 PDB entry)
      Uniprot P32755
    4. 1901023Species Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)
    5. 1901032Species Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)
      Uniprot Q53586
    6. 1901037Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (4 PDB entries)
      Uniprot P93836 33-428 ! Uniprot P93836 63-459
  3. 1901048Catechol 2,3-dioxygenase (metapyrocatechase) [54606] (1 species)
  4. 1901058Homoprotocatechuate 2,3-dioxygenase [89886] (2 species)
    1. 1901059Species Arthrobacter globiformis [TaxId:1665] [89887] (3 PDB entries)
    2. 1901072Species Brevibacterium fuscum [TaxId:47914] [89888] (15 PDB entries)
  5. 1901189automated matches [276310] (2 species)
    not a true protein
    1. 1901190Species Arabidopsis thaliana [TaxId:3702] [276311] (1 PDB entry)
    2. 1901195Species Homo sapiens [TaxId:9606] [279455] (1 PDB entry)

More info for Family d.32.1.3: Extradiol dioxygenases

Timeline for Family d.32.1.3: Extradiol dioxygenases: