Lineage for Family d.26.1.1: FKBP immunophilin/proline isomerase

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 857507Fold d.26: FKBP-like [54533] (3 superfamilies)
    core: beta(2)-alpha-beta(2); antiparallel beta-sheet
  4. 857508Superfamily d.26.1: FKBP-like [54534] (3 families) (S)
  5. 857509Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (16 proteins)

Proteins:

  1. 857510Archaeal FKBP [89879] (1 species)
    contains insert all-beta subdomain; dual function: PPI and chaperone-like activities
  2. 857513Calcineurin (FKBP12.6) [54539] (3 species)
    1. 857514Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [54542] (1 PDB entry)
    2. 857516Species Cow (Bos taurus) [TaxId:9913] [54541] (1 PDB entry)
    3. 857518Species Human (Homo sapiens) [TaxId:9606] [54540] (1 PDB entry)
  3. 857520FK-506 binding protein (FKBP12), an immunophilin [54536] (2 species)
    cis-trans prolyl-isomerase
    1. 857521Species Cow (Bos taurus) [TaxId:9913] [54538] (2 PDB entries)
    2. 857524Species Human (Homo sapiens) [TaxId:9606] [54537] (33 PDB entries)
  4. 857573FKB-6, N-terminal domain [102864] (1 species)
  5. 857576FKBP13 [110870] (1 species)
  6. 857588FKBP25 [54543] (1 species)
  7. 857591FKBP51, N-terminal domains [82621] (2 species)
    duplication: tandem repeat of two FKBP domains
    1. 857592Species Human (Homo sapiens) [TaxId:9606] [82622] (1 PDB entry)
    2. 857595Species Monkey (Saimiri boliviensis) [TaxId:27679] [82623] (1 PDB entry)
  8. 857598FKBP52, N-terminal domains [82619] (1 species)
  9. 857610FKBP59-I, N-terminal domain [54545] (1 species)
  10. 857614Macrophage infectivity potentiator protein (MIP) [64250] (2 species)
    contains all-alpha dimerisation subdomain in the N-terminal extension
    1. 857615Species Legionella pneumophila [TaxId:446] [64251] (1 PDB entry)
    2. 857617Species Trypanosoma cruzi [TaxId:5693] [75387] (1 PDB entry)
  11. 857619Mitotic rotamase PIN1, domain 2 [54547] (2 species)
    Domain 1 is a WW-domain
    1. 857620Species Human (Homo sapiens) [TaxId:9606] [54548] (7 PDB entries)
    2. 857628Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [75386] (1 PDB entry)
  12. 857630Parvulin [64248] (1 species)
  13. 857634Parvulin 10 (rotamase C) [89877] (1 species)
  14. 857638Peptidyl-prolyl cis-trans isomerase FkpA [102866] (1 species)
    similar to MIP; contains all-alpha dimerisation subdomain in the N-terminal extension
  15. 857645Porin chaperone SurA, PPIase domains [82624] (1 species)
  16. 857662Trigger factor PPIase domain [75388] (3 species)
    1. 857663Species Escherichia coli [TaxId:562] [89881] (3 PDB entries)
      Uniprot P22257
    2. 857668Species Mycoplasma genitalium [TaxId:2097] [75389] (1 PDB entry)
    3. 857670Species Vibrio cholerae [TaxId:666] [110869] (1 PDB entry)
      Uniprot Q9KQS5

More info for Family d.26.1.1: FKBP immunophilin/proline isomerase

Timeline for Family d.26.1.1: FKBP immunophilin/proline isomerase: