SCOPe 2.02: Family d.15.2.1: CAD domain

Lineage for Family d.15.2.1: CAD domain

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.2: CAD & PB1 domains [54277] (2 families)
   contain extra helix; similar heterodimerization modes; possibly related to the ubiquitin-like superfamily

5. Family d.15.2.1: CAD domain [54278] (3 proteins)

Proteins:

1. Caspase-activated DNase (CAD), DFF40, N-terminal domain [54281] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [64223] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [54282] (2 PDB entries)

2. Cell death-inducing effector B (CIDE-B), N-terminal domain [54279] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54280] (1 PDB entry)

3. Inhibitor of caspase-activated DNase (ICAD), DFF45, N-terminal domain [54283] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [64224] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [54284] (1 PDB entry)

More info for Family d.15.2.1: CAD domain

Timeline for Family d.15.2.1: CAD domain:

• Family d.15.2.1: CAD domain first appeared (with stable ids) in SCOP 1.55
  
• Family d.15.2.1: CAD domain appears in SCOPe 2.01
  
• Family d.15.2.1: CAD domain appears in SCOPe 2.03
  
• Family d.15.2.1: CAD domain appears in the current release, SCOPe 2.08